ReviewTrends in immunology2010
Eosinophils and allergic airway disease: there is more to the story.
Review in Trends in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- Adjuvant Effect ofPharmaceuticals (Basel, Switzerland) · 2024Article
- Eosinophils and childhood asthma.Clinical and experimental pediatrics · 2021Article
- Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A.Journal of immunology (Baltimore, Md. : 1950) · 2020Article
- The Innate Immune Cross Talk between NK Cells and Eosinophils Is Regulated by the Interaction of Natural Cytotoxicity Receptors with Eosinophil Surface Ligands.Frontiers in immunology · 2017Article
- Tumour-Associated Tissue Eosinophilia in Oral Squamous Cell Carcinoma- A Boon or a Bane?Journal of clinical and diagnostic research : JCDR · 2016Article
- Asthma and risk of lethal prostate cancer in the Health Professionals Follow-Up Study.International journal of cancer · 2015Article
- Eosinophils Modulate CD4(+) T Cell Responses via High Mobility Group Box-1 in the Pathogenesis of Asthma.Allergy, asthma & immunology research · 2015Article
- Eosinophilic chronic rhinosinusitis in East Asians.World journal of clinical cases · 2014Review
- Complement components as potential therapeutic targets for asthma treatment.Respiratory medicine · 2014Review
- A combination of predispositions and exposures as responsible for acute eosinophilic pneumonia.Multidisciplinary respiratory medicine · 2014Article
- Lymphocyte-based model systems for allergy research: a historic overview.International archives of allergy and immunology · 2014Review
- Peptidoglycan recognition protein 1 promotes house dust mite-induced airway inflammation in mice.American journal of respiratory cell and molecular biology · 2013Article
- Eosinophil apoptosis and clearance in asthma.Journal of cell death · 2013Review
- Assessment of murine lung mechanics outcome measures: alignment with those made in asthmatics.Frontiers in physiology · 2012Article
- IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro.PloS one · 2012Article
- Infection, eosinophilia and childhood asthma.Asia Pacific allergy · 2012Article
- What targeting eosinophils has taught us about their role in diseases.The Journal of allergy and clinical immunology · 2010Review
- Environmental exposures and airway inflammation in young thoroughbred horses.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The eosinophil has been perceived as a terminal effector cell in allergic airway diseases. However, recent work has shown that this multifunctional cell could be more involved in the initial stages of allergic disease development than was previously thought, particularly with regard to the ability of the eosinophil to modulate T-cell responses. In this review, we discuss recent advances that suggest that eosinophils can present antigen to naïve as well as to antigen-experienced T cells, induce T helper 2 cell development, cytokine production or both, and affect T-cell migration to sites of inflammation. These findings are changing the way that eosinophil function in disease is perceived, and represent a shift in the dogma of allergic disease development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.