ArticleVaccine2009
Evaluating the cost-effectiveness of rabies post-exposure prophylaxis: a case study in Tanzania.
Article in Vaccine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pharmacoeconomics and its implication on priority-setting for essential medicines in Tanzania: a systematic review.BMC medical informatics and decision making · 2012Pooled it
- Cost-utility analysis of pre-exposure prophylaxis rabies vaccine in 5-year-old children in Thailand.BMJ global health · 2026Article
- Routine childhood rabies pre-exposure prophylaxis can be cost effective in low- and middle-income countries.Vaccine · 2025Article
- Benefit-cost analysis of coordinated strategies for control of rabies in Africa.Nature communications · 2023Article
- A Cost-Effectiveness Analysis of Pre-Exposure Prophylaxis to Avert Rabies Deaths in School-Aged Children in India.Vaccines · 2022Article
- Roles of traditional medicine and traditional healers for rabies prevention and potential impacts on post-exposure prophylaxis: A literature review.PLoS neglected tropical diseases · 2022Review
- Benefit-Risk Assessment of the French Surveillance Protocol of Apparently Healthy Biting Dogs and Cats for Human Rabies Prevention.Veterinary sciences · 2021Article
- Cost-effectiveness of the national dog rabies prevention and control program in Mexico, 1990-2015.PLoS neglected tropical diseases · 2021Article
- Article
- A cross-sectional study of awareness and practices regarding animal bites in rural community, North India.Journal of family medicine and primary care · 2020Article
- Impact of One-Health framework on vaccination cost-effectiveness: A case study of rabies in Ethiopia.One health (Amsterdam, Netherlands) · 2019Article
- Article
- Article
- Human rabies in Côte d'Ivoire 2014-2016: Results following reinforcements to rabies surveillance.PLoS neglected tropical diseases · 2018Observational
- Article
- The evaluation of operating Animal Bite Treatment Centers in the Philippines from a health provider perspective.PloS one · 2018Article
- Dog Bites and Rabies in the Eastern Region of Ghana in 2013-2015: A Call for a One-Health Approach.Journal of tropical medicine · 2018Article
- Effect of counselling on health-care-seeking behaviours and rabies vaccination adherence after dog bites in Haiti, 2014-15: a retrospective follow-up survey.The Lancet. Global health · 2017Article
- Cost-Effectiveness Evaluation of a Novel Integrated Bite Case Management Program for the Control of Human Rabies, Haiti 2014-2015.The American journal of tropical medicine and hygiene · 2017Article
- [Evaluation of Knowledge-Attitudes-Practices of the populations in the health districts of Benoye, Laoukassy, Moundou and South N'Djamena towards canine rabies in Chad].The Pan African medical journal · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Although fatal if untreated, human rabies can be prevented through post-exposure prophylaxis (PEP), which involves a course of vaccination and immunoglobulin administered immediately after exposure. However, high costs and frequent lack of rabies vaccine and immunoglobulin lead to about 55,000 deaths per year worldwide. Using data from a detailed study of rabies in Tanzania, we calculate a cost-effectiveness ratio for PEP when the WHO-recommended Essen regimen, a 5-dose intramuscular vaccination schedule, is adopted. Our analyses indicate a cost-effectiveness ratio for PEP of $27/quality-adjusted life year (QALY) from a health care perspective and $32/QALY from a societal perspective in Tanzania. From both perspectives, it is "very cost-effective" to administer PEP to patients bitten by an animal suspected to be rabid. Moreover, PEP remains "very cost-effective" provided that at least 1% of doses are administered to people who were actually exposed to rabies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.