ReviewFEBS letters2010
tRNA as an active chemical scaffold for diverse chemical transformations.
Review in FEBS letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 63 citations in OpenAlex.
- A single viral enzyme drives tRNA-dependent hypermodification of DNA at adenine.Nature communications · 2026Article
- Chromosomal assembly of the flat oyster (Evolutionary applications · 2022Article
- Evolution and structural variations in chloroplast tRNAs in gymnosperms.BMC genomics · 2021Article
- Transfer RNAs: diversity in form and function.RNA biology · 2021Review
- Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme.RSC chemical biology · 2021Article
- Noncanonical Roles of tRNAs: tRNA Fragments and Beyond.Annual review of genetics · 2020Review
- Analysis of genomic tRNA revealed presence of novel genomic features in cyanobacterial tRNA.Saudi journal of biological sciences · 2020Article
- Review
- Pseudomonas aeruginosa cells attached to a surface display a typical proteome early as 20 minutes of incubation.PloS one · 2017Article
- Detection of a Putative TetR-Like Gene Related toFrontiers in microbiology · 2017Article
- Non-canonical roles of tRNAs and tRNA mimics in bacterial cell biology.Molecular microbiology · 2016Review
- Aminoacyl-tRNA Synthetases in the Bacterial World.EcoSal Plus · 2016Review
- tRNA-Derived Small Non-Coding RNAs in Response to Ischemia Inhibit Angiogenesis.Scientific reports · 2016Article
- Transcriptome-wide measurement of plant RNA secondary structure.Current opinion in plant biology · 2015Review
- Identification of novel small ncRNAs in pollen of tomato.BMC genomics · 2015Article
- Article
- Effect of hydrogen peroxide on the biosynthesis of heme and proteins: potential implications for the partitioning of Glu-tRNA(Glu) between these pathways.International journal of molecular sciences · 2014Article
- The tRNA-dependent biosynthesis of modified cyclic dipeptides.International journal of molecular sciences · 2014Review
- The determination of tRNALeu recognition nucleotides for Escherichia coli L/F transferase.RNA (New York, N.Y.) · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
During protein synthesis, tRNA serves as the intermediary between cognate amino acids and their corresponding RNA trinucleotide codons. Aminoacyl-tRNA is also a biosynthetic precursor and amino acid donor for other macromolecules. AA-tRNAs allow transformations of acidic amino acids into their amide-containing counterparts, and seryl-tRNA(Ser) donates serine for antibiotic synthesis. Aminoacyl-tRNA is also used to cross-link peptidoglycan, to lysinylate the lipid bilayer, and to allow proteolytic turnover via the N-end rule. These alternative functions may signal the use of RNA in early evolution as both a biological scaffold and a catalyst to achieve a wide variety of chemical transformations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.