ArticleCritical care (London, England)2009
Complications of continuous renal replacement therapy in critically ill children: a prospective observational evaluation study.
Article in Critical care (London, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 99 citations in OpenAlex.
- When to stop kidney replacement therapy in critically ill children: current evidence and practical considerations from a pediatric critical care nephrology perspective.Pediatric nephrology (Berlin, Germany) · 2026Article
- Continuous kidney replacement therapy with CARPEDIEMPediatric nephrology (Berlin, Germany) · 2026Article
- Intradialytic hypotension and hemodynamic phenotypes in children following continuous renal replacement therapy initiation.Pediatric research · 2026Observational
- Advanced hemodynamic monitoring: feasibility of leveraging non-invasive electrocardiometry in critically ill pediatric patients requiring continuous kidney replacement therapy.Pediatric nephrology (Berlin, Germany) · 2025Observational
- Enhancing outcomes in pediatric populations with continuous renal replacement therapy: Current multidisciplinary strategies and innovations.Journal of intensive medicine · 2025Review
- Renal replacement therapy in an intensive care unit: guidelines from the SRLF-GFRUP consensus conference.Annals of intensive care · 2025Review
- Effectiveness and feasibility of continuous renal replacement therapy for acute kidney injury in neonates weighing 3 kg or less: a two-centre, retrospective study.BMJ paediatrics open · 2024Article
- New perspectives in pediatric dialysis technologies: the case for neonates and infants with acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2024Article
- Predictors of successful discontinuation of continuous kidney replacement therapy in a pediatric cohort.Pediatric nephrology (Berlin, Germany) · 2023Article
- Clinical characteristics and outcomes of continuous renal replacement therapy performed on younger children weighing up to 10 kg.Turkish journal of medical sciences · 2023Observational
- Contrast-Associated Acute Kidney Injury Requiring Continuous Renal Replacement Therapy in A Neonate with Aortic Stenosis-A Case Report.Pediatric reports · 2023Article
- Risk of ventricular tachycardia and its outcomes in patients undergoing continuous renal replacement therapy due to acute kidney injury.Kidney research and clinical practice · 2023Article
- The relationship between commencement of continuous renal replacement therapy and urine output, fluid balance, mean arterial pressure and vasopressor dose.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2022Article
- Hemodynamic instability during connection to continuous kidney replacement therapy in critically ill pediatric patients.Pediatric nephrology (Berlin, Germany) · 2022Article
- Effect of Phoxilium on prognostic predictors in patients undergoing continuous venovenous hemodiafiltration.Kidney research and clinical practice · 2021Article
- Hemodynamic disturbances and oliguria during continuous kidney replacement therapy in critically ill children.Pediatric nephrology (Berlin, Germany) · 2021Observational
- Prevalence and risk factors of hemodynamic instability associated with preload-dependence during continuous renal replacement therapy in a prospective observational cohort of critically ill patients.Annals of intensive care · 2021Article
- Continuous renal replacement therapy in critically ill children: single-center experienceTurkish journal of medical sciences · 2021Article
- A Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight.Frontiers in pediatrics · 2021Article
- Changes in hemodynamics, renal blood flow and urine output during continuous renal replacement therapies.Scientific reports · 2020Article
Corrections and comments
- Commented on by
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionContinuous renal replacement therapy (CRRT) frequently gives rise to complications in critically ill children. However, no studies have analyzed these complications prospectively. The purpose of this study was to analyze the complications of CRRT in children and to study the associated risk factors.
methodsA prospective, single-centre, observational study was performed in all critically ill children treated using CRRT in order to determine the incidence of complications related to the technique (problems of catheterization, hypotension at the time of connection to the CRRT, hemorrhage, electrolyte disturbances) and their relationship with patient characteristics, clinical severity, need for vasoactive drugs and mechanical ventilation, and the characteristics of the filtration techniques.
resultsOf 174 children treated with CRRT, 13 (7.4%) presented problems of venous catheterization; this complication was significantly more common in children under 12 months of age and in those weighing less than 10 kg. Hypotension on connection to CRRT was detected in 53 patients (30.4%). Hypotension was not associated with any patient or CRRT characteristics. Clinically significant hemorrhage occurred in 18 patients (10.3%); this complication was not related to any of the variables studied. The sodium, chloride, and phosphate levels fell during the first 72 hours of CRRT; the changes in electrolyte levels during the course of treatment were not found to be related to any of the variables analyzed, nor were they associated with mortality.
conclusionsCRRT-related complications are common in children and some are potentially serious. The most common are hypotension at the time of connection and electrolyte disturbances. Strict control and continuous monitoring of the technique are therefore necessary in children on CRRT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.