ReviewThe New phytologist2010
The gene balance hypothesis: implications for gene regulation, quantitative traits and evolution.
Review in The New phytologist, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
154 citing papers in PubMed, 333 citations in OpenAlex.
- A sorghum-anchored pan-grass syntenic gene set in grasses.NAR genomics and bioinformatics · 2026Article
- Heterosis in wheat: mechanisms, benefits, and challenges in hybrid development.Journal of experimental botany · 2026Review
- Review
- Homoeolog expression in polyploid wheat mutants shows limited transcriptional compensation.The New phytologist · 2026Article
- Decades' progress and prospects on maize functional genomics and molecular breeding.Science China. Life sciences · 2025Review
- Quantitative Insights into the Genetic Mechanisms of Crop Heterosis.Advanced genetics (Hoboken, N.J.) · 2025Review
- Essential developmental processes in Physcomitrium patens require distinct levels of total activity provided by functionally redundant PpROP GTPases.The New phytologist · 2025Article
- Spatial variation in the mutation rate within the plant shoot apical meristem.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Effects of Ploidy on Relationship Between Outbreeding Response and Fitness in a Plant Selfing Species.Ecology and evolution · 2025Article
- SPEECHLESS duplication in grasses expands potential for environmental regulation of stomatal development.bioRxiv : the preprint server for biology · 2025Article
- X-chromosome upregulation operates on a gene-by-gene basis at RNA and protein levels.Nature communications · 2025Article
- Nonadditive gene expression contributing to heterosis in partially heterozygous maize hybrids is predominantly regulated from heterozygous regions.The New phytologist · 2025Article
- Independent evolution of betulin biosynthesis in Inonotus obliquus.Scientific reports · 2025Article
- doubletrouble: an R/Bioconductor package for the identification, classification, and analysis of gene and genome duplications.Bioinformatics (Oxford, England) · 2025Article
- Dualistic MADS-box evolution forged legume diversity post-WGD.Frontiers in plant science · 2025Article
- Induced and natural variation affect traits independently in hybrid Populus.G3 (Bethesda, Md.) · 2024Article
- The response to single-gene duplication implicates translation as a key vulnerability in aneuploid yeast.PLoS genetics · 2024Article
- Unlocking the mystery of heterosis opens the era of intelligent rice breeding.Plant physiology · 2024Review
- Compensation of gene dosage on the mammalian X.Development (Cambridge, England) · 2024Review
- Comparative transcriptome analysis provides molecular insights into heterosis of waterlogging tolerance in Chrysanthemum indicum.BMC plant biology · 2024Review
94 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
The gene balance hypothesis states that the stoichiometry of members of multisubunit complexes affects the function of the whole because of the kinetics and mode of assembly. Gene regulatory mechanisms also would be governed by these principles. Here, we review the impact of this concept with regard to the effects on the genetics of quantitative traits, the fate of duplication of genes following polyploidization events or segmental duplication, the basis of aneuploid syndromes, the constraints on cis and trans variation in gene regulation and the potential involvement in hybrid incompatibilities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.