ReviewMolecular diagnosis & therapy2009
Early detection of breast cancer: new biomarker tests on the horizon?
Review in Molecular diagnosis & therapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Enhanced drug delivery with nanocarriers: a comprehensive review of recent advances in breast cancer detection and treatment.Discover nano · 2024Review
- Determine knowledge and belief of Somalian young women about breast cancer and breast self-examination with champion health belief model: a cross-sectional study.BMC medical informatics and decision making · 2022Article
- Resolving breast cancer heterogeneity by searching reliable protein cancer biomarkers in the breast fluid secretome.BMC cancer · 2013Review
- Accurate sensitivity of quantum dots for detection of HER2 expression in breast cancer cells and tissues.Journal of fluorescence · 2013Article
- Expression of the molecular chaperone αB-crystallin in infiltrating ductal breast carcinomas and the significance thereof: an immunohistochemical and proteomics-based strategy.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2012Article
- Article
- Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy.Molecular oncology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When cancer is detected early, patients live longer, require less extensive treatment, and in general fare better than patients with more advanced disease. Breast cancer is the most commonly diagnosed cancer among women. Breast cancer screening through mammography has shown significant mortality reduction in clinical trials through the early detection of disease. This article aims to outline novel methods of indirect and direct detection of breast cancer through biomarkers. Proteomics and gene expression profiling methods will likely be important tools in regard to cancer detection in the future. Blood-based biomarker development is the furthest along and, either in the form of proteins or RNA, shows promise to lead to early detection techniques. Unfortunately, procedures aiming to analyze the breast tissue more directly have not had the desired outcomes thus far for the early detection of breast cancer. Appropriate development of these potential early detection and diagnostic tests is necessary prior to their clinical application, with special attention to their specificity to avoid overdiagnosis.
Indexed as
Identifiers
19925032What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.