Evidence map›Paper›PMID 19923578›Full record

ReviewThe New England journal of medicine2009

Inflammatory bowel disease.

Clara Abraham, Judy H Cho

3 registry-linked trialsAbstract readReview
In one paragraph

Review in The New England journal of medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 1,423 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,423citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04691232 phase1completednot on this mapstarted 2021, after this paper: background citation

Phase I, Open-label, Fast-track Dose-escalation Clinical Trial Exploring the Safety and the Tolerability of Autologous ex Vivo Expanded Regulatory T Cells in Adults With Ulcerative Colitis

TypeinterventionalSponsorUniversity of Erlangen-Nürnberg Medical SchoolRan2021 to 2023Enrolled11ConditionsUlcerative Colitis, Autoimmune DiseasesArmsRegulatory T cells
NCT05967650 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Efficacy of Accelerated Versus Standard Regiment of Hepatitis B Virus Vaccine Among Inflammatory Bowel Disease Patients

TypeinterventionalSponsorAssiut UniversityRan2023 to 2024Enrolled200ConditionsInflammatory Bowel DiseasesArmsstandard hepatitis B vaccine, accelerated HBV Vaccine
NCT06252493 recruitingnot on this mapstarted 2023, after this paper: background citation

Evaluation of PET/MR Enterography for Differentiation of Fibrotic and Inflammatory Strictures in Patients With Crohn's Disease Using a Collagen-binding Radiotracer.

TypeobservationalSponsorMassachusetts General HospitalRan2023 to 2029Enrolled25ConditionsCrohn DiseaseArmsRadiotracer Injection, Contrast Media, Magnetic Resonance, Blood Draw, Glucagon, Imaging
3 · Its place in the literature

Who cites it

1,423 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  3. To eradicate or not?Frontiers in medicine · 2026
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1,363 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Clara AbrahamDepartment of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06520, USA.
Judy H Cho

Funding

YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Yale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI YASUKO IWAKIRI · 1986 to 2026
$31.1M
Inflammatory Bowel Disease Genetics Consortium Data Coordinating CenterU01DK062429 · NIDDK · YALE UNIVERSITY · PI CHO, JUDY H. · 2002 to 2016
$16.8M
Yale University Inflammatory Bowel Disease Genetics Research CenterU01DK062422 · NIDDK · YALE UNIVERSITY · PI Ling-shiang Chuang · 2002 to 2026
$10.8M
Mechanisms of Chronic Nod2-mediated Effects in Human MacrophagesR01DK077905 · NIDDK · YALE UNIVERSITY · PI ABRAHAM, CLARA · 2008 to 2012
$1.7M
Beyond single-point GWAS: genetics of Crohn's disease in Ashkenazi JewsRC1DK086800 · NIDDK · YALE UNIVERSITY · PI CHO, JUDY H. · 2009 to 2010
$998k
Mapping Chromosome 3q Inflammatory Bowel Disease GenesR01DK072373 · NIDDK · YALE UNIVERSITY · PI CHO, JUDY H. · 2006 to 2008
$845k
NCRR NIH HHS UL1 RR024139NIDDK NIH HHS DK P30-34989NIDDK NIH HHS R01 DK072373NIDDK NIH HHS R01DK072373NIDDK NIH HHS R01 DK077905NIDDK NIH HHS R01DK077905NIDDK NIH HHS RC1 DK086800NIDDK NIH HHS U01 DK062422NIDDK NIH HHS U01 DK062429NIDDK NIH HHS U01 DK62429
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunity, InnateAnimalsColitis, UlcerativeCrohn DiseaseHumansInflammatory Bowel DiseasesInterleukin-23Intestinal MucosaMetagenomeT-LymphocytesInterleukin-23

Identifiers

PMID19923578
PMCPMC3491806

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.