Evidence map›Paper›PMID 19923183›Full record

ReviewJournal of virology2010

Early events in Kaposi's sarcoma-associated herpesvirus infection of target cells.

Bala Chandran

Abstract readReview
In one paragraph

Review in Journal of virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Rapid NETosis Is an Effector Mechanism to Combat Ocular Herpes Infection.Investigative ophthalmology & visual science · 2024
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Viruses and Skin Cancer.International journal of molecular sciences · 2021
    Review
  19. Article
  20. Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Bala ChandranH.M. Bligh Cancer Research Laboratories, Dept. of Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA. bala.chandran@rosalindfranklin.edu

Funding

ANTIGENS OF KAPOSIS SARCOMA ASSOCIATED HERPESVIRUSR01CA075911 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI CHANDRAN, BALA · 1998 to 2012
$3.5M
Entry of HHV-8 Into the Target CellsR01AI057349 · NIAID · ROSALIND FRANKLIN UNIV OF MEDICINE &SCI · PI CHANDRAN, BALA · 2005 to 2009
$1.6M
NCI NIH HHS CA 075911NCI NIH HHS R01 CA075911NIAID NIH HHS AI057349NIAID NIH HHS R01 AI057349
6 · The paper itself

Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV), the most recently identified member of the herpesvirus family, infects a variety of target cells in vitro and in vivo. This minireview surveys current information on the early events of KSHV infection, including virus-receptor interactions, involved envelope glycoproteins, mode of entry, intracellular trafficking, and initial viral and host gene expression programs. We describe data supporting the hypothesis that KSHV manipulates preexisting host cell signaling pathways to allow successful infection. The various signaling events triggered by infection, and their potential roles in the different stages of infection and disease pathogenesis, are summarized.

Indexed as

B-LymphocytesCells, CulturedDNA, ViralEndothelial CellsFocal Adhesion Protein-Tyrosine KinasesGene Expression Regulation, ViralHerpesviridae InfectionsHerpesvirus 8, HumanHumansKeratinocytesMicrotubulesMonocytesPhosphatidylinositol 3-KinasesrhoA GTP-Binding ProteinSignal Transductionsrc-Family KinasesDNA, ViralFocal Adhesion Protein-Tyrosine KinasesPhosphatidylinositol 3-KinasesrhoA GTP-Binding Proteinsrc-Family KinasesViral Envelope Proteins

Identifiers

PMID19923183
PMCPMC2820927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.