ArticleAddiction (Abingdon, England)2010
Estimating driver risk using alcohol biomarkers, interlock blood alcohol concentration tests and psychometric assessments: initial descriptives.
Article in Addiction (Abingdon, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Biomolecules and Biomarkers Used in Diagnosis of Alcohol Drinking and in Monitoring Therapeutic Interventions.Biomolecules · 2015Pooled it
- Phosphatidylethanol in blood as a marker of chronic alcohol use: a systematic review and meta-analysis.International journal of molecular sciences · 2012Pooled it
- Use of continuous transdermal alcohol monitoring during a contingency management procedure to reduce excessive alcohol use.Drug and alcohol dependence · 2014Trial
- The effects of closer monitoring on driver compliance with interlock restrictions.Accident; analysis and prevention · 2011Trial
- Determination by UHPLC-QTOF-HRMS of Phosphatidylethanol (PEth) in Dried Blood Spots: Method Validation and Practical Application of a Rising Alcohol Abuse Biomarker With Minimally Invasive Sampling.Biomedical chromatography : BMC · 2025Article
- Cannabis Adaptation During and After Alcohol Ignition Interlock Device Installation: A Longitudinal Study.Journal of studies on alcohol and drugs · 2022Article
- Mixed-methods trial of a phosphatidylethanol-based contingency management intervention to initiate and maintain alcohol abstinence in formerly homeless adults with alcohol use disorders.Contemporary clinical trials communications · 2021Article
- Convicted drinking and driving offenders: Comparing alcohol use before and after the pandemic outbreak.Alcoholism, clinical and experimental research · 2021Article
- Changes in Alcohol Use and Drinking and Driving Outcomes From Before Arrest for Driving Under the Influence to After Interlock Removal.Alcoholism, clinical and experimental research · 2021Article
- Fatty acid ethyl esters in meconium: A biomarker of fetal alcohol exposure and effect.Experimental biology and medicine (Maywood, N.J.) · 2021Article
- The Clinical Course of Alcohol Use Disorder Depicted by Digital Biomarkers.Frontiers in digital health · 2021Article
- Typologies of Drivers Convicted of Driving Under the Influence of Alcohol as Predictors of Alcohol Ignition Interlock Performance.Alcoholism treatment quarterly · 2021Article
- Urinary Ethyl Glucuronide as Measure of Alcohol Consumption and Risk of Cardiovascular Disease: A Population-Based Cohort Study.Journal of the American Heart Association · 2020Article
- Driver experiences with the alcohol ignition interlock: Comparing successful and poor performers.Traffic injury prevention · 2020Article
- The impact of interlock installation on driving behavior and drinking behavior related to driving.Traffic injury prevention · 2020Article
- Potential for cannabis adaptation among participants in a drunk driving intervention.Journal of substance use · 2020Article
- Applications ofChinese herbal medicines · 2019Article
- Cross-Culture Adaptation and Psychometric Properties of the DrInC Questionnaire in Tanzanian Swahili.Frontiers in public health · 2018Article
- Mandating Treatment Based on Interlock Performance: Evidence for Effectiveness.Alcoholism, clinical and experimental research · 2016Article
- Characterization of the Pharmacokinetics of Phosphatidylethanol 16:0/18:1 and 16:0/18:2 in Human Whole Blood After Alcohol Consumption in a Clinical Laboratory Study.Alcoholism, clinical and experimental research · 2016Article
Corrections and comments
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Authors and funding
8 authors at 7 institutions in 5 countries.
Funding
Abstract
aimTo identify alcohol biomarker and psychometric measures that relate to drivers' blood alcohol concentration (BAC) patterns from ignition interlock devices (IIDs). DESIGN, SETTING, PARTICIPANTS, MEASUREMENTS: In Alberta, Canada, 534 drivers, convicted of driving under the influence of alcohol (DUI), installed IIDs and agreed to participate in a research study. IID BAC tests are an established proxy for predicting future DUI convictions. Three risk groups were defined by rates of failed BAC tests. Program entry and follow-up blood samples (n = 302, 171) were used to measure phosphatidyl ethanol (PETH), carbohydrate deficient transferrin (%CDT), gamma glutamyltransferase (GGT) and other biomarkers. Program entry urine (n = 130) was analyzed for ethyl glucuronide (ETG) and ethyl sulphate (ETS). Entry hair samples were tested for fatty acid ethyl esters (FAEE) (n = 92) and ETG (n = 146). Psychometric measures included the DSM-4 Diagnostic Interview Schedule Alcohol Module, Alcohol Use Disorders Identification Test (AUDIT), the time-line follow-back (TLFB), the Drinker Inventory of Consequences (DRINC) and the Temptation and Restraint Inventory (TRI).
findingsExcept for FAEE, all alcohol biomarkers were related significantly to the interlock BAC test profiles; higher marker levels predicted higher rates of interlock BAC test failures. PETH, the strongest with an overall analysis of variance F ratio of 35.5, had significant correlations with all nine of the other alcohol biomarkers and with 16 of 19 psychometric variables. Urine ETG and ETS were correlated strongly with the IID BAC tests.
conclusionsThe findings suggest that several alcohol biomarkers and assessments could play an important role in the prediction and control of driver alcohol risk when re-licensing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.