Evidence map›Paper›PMID 19921298›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2010

Anaemia is an independent predictor of death in patients hospitalized for acute heart failure.

Stephan von Haehling, Joerg C Schefold, Lea Majc Hodoscek, Wolfram Doehner, Marwan Mannaa, Stefan D Anker, Mitja Lainscak

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Iron therapy in anaemic adults without chronic kidney disease.The Cochrane database of systematic reviews · 2014
    Pooled it
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  18. Anemia is associated with an increased central venous pressure and mortality in a broad spectrum of cardiovascular patients.Clinical research in cardiology : official journal of the German Cardiac Society · 2014
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Stephan von HaehlingApplied Cachexia Research, Department of Cardiology, Charité Medical School, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany. stephan.von.haehling@web.de
Joerg C Schefold
Lea Majc Hodoscek
Wolfram Doehner
Marwan Mannaa
Stefan D Anker
Mitja Lainscak
Charité - Universitätsmedizin Berlin · DEPomurski muzej Murska Sobota · SIIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute heart failure is associated with a poor prognosis. It is important to identify patients at increased risk of adverse events. The presence of anaemia could help in this regard. METHODS AND

resultsAdmission charts of 627 patients (325 female) with acute heart failure were analysed; 182 patients (29%) fulfilled the World Health Organization criteria of anaemia [haemoglobin (Hb) < 13.0 in men, <12.0 g/dl in women], 87 (48%) of them were female. Anaemic patients were older than non-anaemics (p = 0.04), had lower systolic and diastolic blood pressure (both p < 0.05), had higher creatinine (p < 0.01), and stayed longer in hospital (p = 0.0005). Patients were followed-up for a mean of 61 months or until death. A total of 387 patients (61.7%) died during follow-up. Anaemia was an independent predictor of death in this cohort. Patients with moderate or severe anaemia (Hb < 12 in men or <11 g/dl in women) had a significantly increased 12-month mortality after adjusting for age, New York Heart Association class, systolic and diastolic blood pressure, and creatinine (hazard ratio 1.5, 95% confidence interval 1.1-2.0, p = 0.01).

conclusionAnaemia is a frequent co-morbidity in patients with acute heart failure. Moderate to severe anaemia is an independent predictor of death in these patients.

Indexed as

Proportional Hazards ModelsAcute DiseaseAgedAnemiaComorbidityFemaleGermanyHeart FailureHumansIncidenceMalePatient AdmissionRisk AssessmentRisk FactorsSurvival AnalysisSurvival Rate

Identifiers

PMID19921298
OpenAlexW2147959874

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.