Evidence map›Paper›PMID 19918155›Full record

ArticleNursing research

Methodological issues in trials of complementary and alternative medicine interventions.

Alla Sikorskii, Gwen Wyatt, David Victorson, Gwen Faulkner, Mohammad Hossein Rahbar

2 registry-linked trialsAbstract read
In one paragraph

Article in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01577420 nacompletednot on this map

Reflexology: An Intervention for Advanced Breast Cancer

TypeinterventionalSponsorMichigan State UniversityRan2005 to 2010Enrolled451ConditionsBreast CancerArmsReflexology Sessions, Placebo Sessions
NCT02863302 naunknown statusnot on this map

Reflexology Treatment for Newly Diagnosed AML Patients, Can it Reduce GI Tract Side Effects, and Improve and Improve Patients Mood.

TypeinterventionalSponsorRambam Health Care CampusRan2017 to 2018Enrolled50ConditionsAcute Myeloid LeukemiaArmsReflexology treatment
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Pilot Study of Medical Misinformation Perceptions and Training Among Practitioners in North Carolina (USA).Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alla SikorskiiDepartment of Statistics and Probability, College of Natural Science, Michigan State University, East Lansing, MI, 48824, USA. sikorska@stt.msu.edu
Gwen Wyatt
David Victorson
Gwen Faulkner
Mohammad Hossein Rahbar

Funding

Reflexology: An Intervention for Advanced Breast CancerR01CA104883 · NCI · MICHIGAN STATE UNIVERSITY · PI WYATT, GWEN KARILYN · 2005 to 2009
$2.3M
NCI NIH HHS R01 CA104883
6 · The paper itself

Abstract

backgroundComplementary and alternative medicine (CAM) use is widespread among cancer patients. Information on safety and efficacy of CAM therapies is needed for both patients and healthcare providers. Well-designed randomized clinical trials of CAM therapy interventions can inform both clinical research and practice.

objectivesThe aim of this study was to review important issues that affect the design of randomized clinical trials for CAM interventions.

methodsUsing the methods component of the Consolidated Standards for Reporting Trials as a guiding framework and a National Cancer Institute-funded reflexology study as an exemplar, methodological issues related to participants, intervention, objectives, outcomes, sample size, randomization, blinding, and statistical methods were reviewed. DISCUSSION: Trials of CAM interventions designed and implemented according to appropriate methodological standards will facilitate the needed scientific rigor in CAM research. Interventions in CAM can be tested using proposed methodology, and the results of testing will inform nursing practice in providing safe and effective supportive care and in improving the well-being of patients.

Indexed as

Complementary TherapiesNursingRandomized Controlled Trials as TopicResearch Design

Identifiers

PMID19918155
PMCPMC2880328

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.