Evidence map›Paper›PMID 19917535›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2009

Animal models of breast cancer for the study of pathogenesis and therapeutic insights.

Angels Sierra

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Angels SierraInstitut d'Investigació Biomèdica de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain. asierra@idibell.cat

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of oncogenes and inactivation of tumour suppressor genes are common events during breast cancer initiation and progression and often determine treatment responsiveness. Indeed, these events need to be recreated in in vitro systems and in mouse cancer models in order to unravel the molecular mechanisms involved in breast cancer initiation and metastasis and assess their possible impact on responses to anticancer drugs. Optical-based imaging models are used to investigate and to follow important tumour progression processes. Moreover, the development of novel anticancer strategies requires more sensitive and less invasive methods to detect and monitor in vivo drug responses in breast cancer models. This review highlights some of the current strategies for modelling breast cancer in vitro and in the mouse, in order to answer biological or translational questions about human breast malignancies.

Indexed as

Disease Models, AnimalAnimalsAntineoplastic AgentsBreast NeoplasmsDisease ProgressionExtracellular MatrixFemaleHumansMammary Neoplasms, AnimalMedical OncologyMiceNeoplasm MetastasisSignal TransductionAntineoplastic Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.