ArticleWorld journal of gastroenterology2009
Association between Helicobacter pylori seropositivity and digestive tract cancers.
Article in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Should we pay more attention to the potential link betweenWorld journal of gastroenterology · 2024Pooled it
- Risk for Colorectal Neoplasia in Patients With Helicobacter pylori Infection: A Systematic Review and Meta-analysis.Clinical and translational gastroenterology · 2020Pooled it
- Helicobacter pylori infection and esophageal cancer risk: an updated meta-analysis.World journal of gastroenterology · 2013Pooled it
- Article
- Review
- Role ofWorld journal of gastroenterology · 2024Article
- Prevalence ofWorld journal of gastroenterology · 2024Observational
- Non-Acid Fluid Exposure and Esophageal Squamous Cell Carcinoma.Digestive diseases and sciences · 2022Review
- Esophagogastric junction adenocarcinoma shares characteristics with gastric adenocarcinoma: Literature review and retrospective multicenter cohort study.Annals of gastroenterological surgery · 2021Review
- Article
- Helicobacter pylori and colorectal cancer-A bacterium going abroad?PLoS pathogens · 2019Article
- Systematic Review with Meta-analysis: Association of Helicobacter pylori Infection with Esophageal Cancer.Gastroenterology research and practice · 2019Review
- Helicobacter Pylory infection in patients with esophageal squamous cell carcinoma.Clinics (Sao Paulo, Brazil) · 2017Article
- Oesophageal adenocarcinoma and gastric cancer: should we mind the gap?Nature reviews. Cancer · 2016Review
- Article
- The human microbiome and surgical disease.Annals of surgery · 2011Article
- PCR-based genotyping of Helicobacter pylori of Gambian children and adults directly from biopsy specimens and bacterial cultures.Gut pathogens · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo explore the role of Helicobacter pylori (H pylori) infection on the risk of digestive tract cancers.
methodsIn total, 199 oral squamous-cell carcinoma (SCC), 317 esophageal SCC, 196 gastric cardia and non-cardia adenocarcinoma and 240 colon adenocarcinoma patients were recruited for serum tests of H pylori infection. Two hospital- and one community-based control groups were used for the comparisons. H pylori seropositivity was determined by an enzyme linked immunosorbent assay method against H pylori IgG.
resultsPresence of H pylori infection was significantly inversely associated with esophageal SCC [adjusted odds ratio (AOR): 0.315-0.472, all P-value < 0.05] but positively associated with gastric adenocarcinoma (both cardia and non-cardia) (AOR: 1.636-3.060, all P-value < 0.05) in comparison to the three control groups. Similar results were not found in cancers of the oral cavity and colon.
conclusionOur findings support the finding that H pylori seropositivity is inversely associated with esophageal SCC risk, but increases the risk of gastric cardia adenocarcinoma.
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