ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2010
A 12-week regimen of caloric restriction improves levels of adipokines and pro-inflammatory cytokines in Korean women with BMIs greater than 23 kg/m2.
Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Different berries and berry fractions have various but slightly positive effects on the associated variables of metabolic diseases on overweight and obese women.European journal of clinical nutrition · 2011Trial
- The Role of Organokines in Obesity and Type 2 Diabetes and Their Functions as Molecular Transducers of Nutrition and Exercise.Metabolites · 2023Review
- Using Intermittent Fasting as a Non-pharmacological Strategy to Alleviate Obesity-Induced Hypothalamic Molecular Pathway Disruption.Frontiers in nutrition · 2022Review
- Calorie Restriction as a New Treatment of Inflammatory Diseases.Advances in nutrition (Bethesda, Md.) · 2021Review
- Relative fat mass at baseline and its early change may be a predictor of incident nonalcoholic fatty liver disease.Scientific reports · 2020Article
- The effect of Ramadan fasting on quiescent systemic lupus erythematosus (SLE) patients' disease activity, health quality of life and lipid profile: a pilot study.Rheumatology international · 2015Observational
- Obesity, immunomodulation and chronic kidney disease.Current opinion in pharmacology · 2013Review
- Contribution of gender and body fat distribution to inflammatory marker concentrations in apparently healthy young adults.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2012Article
- Caloric restriction and chronic inflammatory diseases.Oral diseases · 2012Review
- Postdiagnosis diet quality is inversely related to a biomarker of inflammation among breast cancer survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2010Article
- Kinetic assessment and therapeutic modulation of metabolic and inflammatory profiles in mice on a high-fat and cholesterol diet.PPAR research · 2010Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAdipose tissue mass (ATM) is an important source of adipokines. Increases in ATM contribute to chronic low-grade inflammation characterized by high levels of pro-inflammatory cytokines. We investigated the effects of body fat reduction on blood levels of adipokines and pro-inflammatory cytokines in Korean women with BMIs >23 kg/m(2).
methodsA total of 46 healthy women participated in the study. A registered dietician supervised the subjects as they conformed to a program of caloric restriction during a 12-week experimental period. Anthropometric assessments were carried out, and blood levels of lipids, adipokines, and pro-inflammatory cytokines were analyzed at the beginning and the end of the experiment.
resultsBody weight and body fat mass decreased significantly in our subjects after 12 weeks of caloric restriction (p < 0.001). Blood levels of triacylglycerol were significantly reduced in accordance with body fat reduction. However, the other blood lipid parameters were unchanged. Adipokine, leptin, and visfatin levels decreased significantly, while adiponectin increased significantly (p < 0.05). Levels of pro-inflammatory cytokines TNF-alpha and IFN-gamma were significantly reduced (p < 0.05).
conclusionsOur results indicate that body fat reduction via caloric restriction positively affects the blood levels of adipokines and pro-inflammatory cytokines.
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