ArticleAging health2008
Epidemiology of HIV and response to antiretroviral therapy in the middle aged and elderly.
Article in Aging health, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Sex Differences in HIV Testing among Older Adults in Sub-Saharan Africa: A Systematic Review.BioMed research international · 2021Pooled it
- The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV.The Journal of frailty & aging · 2019Trial
- Changes in multimorbidity burden over a 3-5 year period among people with HIV.Frontiers in systems biology · 2023Article
- Aortic aneurysms and markers of platelet activation, hemostasis, and endothelial disruption in people living with HIV.Frontiers in immunology · 2023Article
- Article
- Challenges with seeking HIV care services: perspectives of older adults infected with HIV in western Kenya.BMC public health · 2019Article
- HIV testing and counselling experiences: a qualitative study of older adults living with HIV in western Kenya.BMC geriatrics · 2018Article
- Effect of age and level of education on neurocognitive impairment in HIV positive Zambian adults.Neuropsychology · 2018Article
- HIV primary care by the infectious disease physician in the United States - extending the continuum of care.AIDS care · 2018Article
- Observational
- Comparing longitudinal CD4 responses to cART among non-perinatally HIV-infected youth versus adults: Results from the HIVRN Cohort.PloS one · 2017Article
- Treatment Outcomes Among Older Human Immunodeficiency Virus-Infected Adults in Nigeria.Open forum infectious diseases · 2017Article
- Future challenges for clinical care of an ageing population infected with HIV: a modelling study.The Lancet. Infectious diseases · 2015Article
- The lifetime medical cost savings from preventing HIV in the United States.Medical care · 2015Article
- HIV-associated anemia after 96 weeks on therapy: determinants across age ranges in Uganda and Zimbabwe.AIDS research and human retroviruses · 2014Article
- A review of cardiovascular and renal function monitoring: a consideration of older adults with HIV.HIV/AIDS (Auckland, N.Z.) · 2013Review
- Polypharmacy in the HIV-infected older adult population.Clinical interventions in aging · 2013Review
- HIV and Menopause: A Systematic Review of the Effects of HIV Infection on Age at Menopause and the Effects of Menopause on Response to Antiretroviral Therapy.Obstetrics and gynecology international · 2013Review
- Article
- Aging with HIV in Africa: the challenges of living longer.AIDS (London, England) · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
HIV is increasing in prevalence in the middle aged and older population owing to both increased longevity, and new infections in these populations. Highly active antiretrorival therapy (HAART) therapy may be less effective at restoring immune function in older patients compared with younger patients. There are significant toxicities associated with HAART therapy that, combined with decreased renal and liver function in older patients, may be more problematic in older HIV-infected patients. Comorbid disease is becoming an increasing problem with coadministration of multiple drugs and significant drug-drug interactions. Psychosocial issues in the older patient are often different than those in younger HIV-infected patients and providers should try to address these issues early. Finally, future research should work to identify the ideal timing and type of HAART regimens for older HIV-infected individuals.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.