ArticlePloS one2009
Detection of B. anthracis spores and vegetative cells with the same monoclonal antibodies.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 38 citations in OpenAlex.
- TrackingACS omega · 2026Review
- Increased Excess Intracellular Cyclic di-AMP Levels Impair Growth and Virulence of Bacillus anthracis.Journal of bacteriology · 2020Article
- Detection and Identification ofMicroorganisms · 2020Review
- Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies.Viruses · 2019Article
- LysPBC2, a Novel Endolysin Harboring a Bacillus cereus Spore Binding Domain.Applied and environmental microbiology · 2019Article
- Development of a double-antibody sandwich ELISA for rapid detection of Bacillus Cereus in food.Scientific reports · 2016Article
- Immuno capture PCR for rapid and sensitive identification of pathogenic Bacillus anthracis.World journal of microbiology & biotechnology · 2013Article
- Existence of separate domains in lysin PlyG for recognizing Bacillus anthracis spores and vegetative cells.Antimicrobial agents and chemotherapy · 2012Article
- Fast and sensitive detection of Bacillus anthracis spores by immunoassay.Applied and environmental microbiology · 2012Article
- Real-time polymerase chain reaction assay for rapid and sensitive detection of anthrax spores in spiked soil and talcum powder.Folia microbiologica · 2012Article
- Rugged single domain antibody detection elements for Bacillus anthracis spores and vegetative cells.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacillus anthracis, the causative agent of anthrax disease, could be used as a biothreat reagent. It is vital to develop a rapid, convenient method to detect B. anthracis. In the current study, three high affinity and specificity monoclonal antibodies (mAbs, designated 8G3, 10C6 and 12F6) have been obtained using fully washed B. anthracis spores as an immunogen. These mAbs, confirmed to direct against EA1 protein, can recognize the surface of B. anthracis spores and intact vegetative cells with high affinity and species-specificity. EA1 has been well known as a major S-layer component of B. anthracis vegetative cells, and it also persistently exists in the spore preparations and bind tightly to the spore surfaces even after rigorous washing. Therefore, these mAbs can be used to build a new and rapid immunoassay for detection of both life forms of B. anthracis, either vegetative cells or spores.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.