ArticleThe New England journal of medicine2009
The HALTS trial--halting atherosclerosis or halted too early?
Article in The New England journal of medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100 667 Patients.Circulation · 2020Pooled it
- Cholesterol treatment patterns and cardiovascular clinical outcomes associated with colesevelam HCl and ezetimibe.Drugs & aging · 2014Article
- Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol.PloS one · 2013Article
- Inhibition of cholesterol absorption: targeting the intestine.Pharmaceutical research · 2012Review
- Ezetimibe therapy: mechanism of action and clinical update.Vascular health and risk management · 2012Review
- Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2011Article
- Statins in combinations: from ARBITER-6 HALTS to ACCORD--what works?Current atherosclerosis reports · 2011Article
- Effects of niacin on atherosclerosis and vascular function.Current opinion in cardiology · 2011Review
- Further opportunities for cost reduction of medical care.Journal of community health · 2010Article
- The utility of cardiopulmonary exercise testing to detect and track early-stage ischemic heart disease.Mayo Clinic proceedings · 2010Article
- Effect of extended-release niacin or ezetimibe on carotid intimal thickness: the ARBITER-HALTS Study.Current atherosclerosis reports · 2010Article
- Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.Drug, healthcare and patient safety · 2010Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
19915216What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.