Evidence map›Paper›PMID 19914288›Full record

ReviewNeuroscience and biobehavioral reviews2010

Psychophysiological biomarkers of workplace stressors.

Tarani Chandola, Alexandros Heraclides, Meena Kumari

Registry-linked trialAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06695715 (Effect of Heart Rate Variability Biofeedback, Interoceptive Training, and Mindfulness on Stress Reduction in the University of Seville Academic Community), which is not on this map. Cited by 90 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06695715 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effect of Heart Rate Variability Biofeedback, Interoceptive Training, and Mindfulness on Stress Reduction in the University of Seville Academic Community (Faculty, Administrative Staff, and Students)

TypeinterventionalSponsorUniversity of SevilleRan2025 to 2026Enrolled120ConditionsStress, AnxietyArmsMindfulness Training Program, HRV Biofeedback, Interoception Training
3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. HRV-Based Training for Improving VOInternational journal of environmental research and public health · 2020
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tarani ChandolaUCL International Institute of Health and Society, UCL Department of Epidemiology and Public Health, University College London, London, United Kingdom. t.chandola@ucl.ac.uk
Alexandros Heraclides
Meena Kumari

Funding

CHANGES IN HEALTH: SOCIO-ECONOMIC STATUS AND PATHWAYSR37AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G · 1999 to 2008
$4.3M
Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
SOCIAL FACTORS INFLUENCING MEDICAL OUTCOME MEASURESR01HS006516 · AHRQ · UNIVERSITY OF LONDON · PI MARMOT, MICHAEL G · 1990 to 1995
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AHRQ HHS HS06516British Heart Foundation RG/07/008/23674Medical Research Council G0100222Medical Research Council G0902037Medical Research Council G19/35Medical Research Council G8802774NHLBI NIH HHS HL36310NHLBI NIH HHS R01 HL036310NIA NIH HHS AG13196NIA NIH HHS R01 AG013196NIA NIH HHS R37 AG013196
6 · The paper itself

Abstract

unlabelledWorkplace stressors are associated with greater coronary heart disease risk, although there is debate over the psychophysiological consequences of work stress. This study builds on recent reviews and examines the literature linking work stress with sympatho-adrenal biomarkers (plasma catecholamines and heart rate variability) and HPA axis biomarkers - the post-morning profile of cortisol.

methodsRelevant studies using appropriate search terms were searched using the bibliographic databases PubMed, Embase, Biosys and Toxline. Four studies on plasma catecholamines, 10 studies on heart rate variability, and 16 studies on post-morning cortisol were reviewed.

resultsIn the majority of studies that examined the association of HRV and work stress, greater reports of work stress is associated with lower heart rate variability. The findings for plasma catecholamines and cortisol secretion are less clear cut and suffer from poorer quality of studies in general.

conclusionThere is evidence that work stress is related to elevated stress responses in terms of sympatho-adrenal and HPA axis biomarkers.

Indexed as

BiomarkersHealthHeart RateHumansHydrocortisoneHypothalamo-Hypophyseal SystemNeurosecretory SystemsPituitary-Adrenal SystemPsychophysiologyStress, PsychologicalSympathetic Nervous SystemWorkplaceBiomarkersHydrocortisone

Identifiers

PMID19914288
PMCPMC2891393

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.