ArticleHealth and quality of life outcomes2009
Urinary and sexual outcomes in long-term (5+ years) prostate cancer disease free survivors after radical prostatectomy.
Article in Health and quality of life outcomes, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 72 citations in OpenAlex.
- Initial results with an absorbable urologic scaffold to mitigate early urinary incontinence following radical prostatectomy: the ARID study.World journal of urology · 2026Trial
- Electroacupuncture in Patients With Early Urinary Incontinence After Radical Prostatectomy: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Prehabilitative versus rehabilitative exercise in prostate cancer patients undergoing prostatectomy.Journal of cancer research and clinical oncology · 2023Trial
- Couple-focused interventions for men with localized prostate cancer and their spouses: A randomized clinical trial.British journal of health psychology · 2019Trial
- [Sexuality of couples 5 years after radical prostatectomy. Sexuality of patients and their partners 1 year postoperatively in sexually active couples].Der Urologe. Ausg. A · 2015Trial
- Sexual bother in men with advanced prostate cancer undergoing androgen deprivation therapy.The journal of sexual medicine · 2014Trial
- Effectiveness of pelvic floor rehabilitation after radical prostatectomy and continence recovery in relation to surgical technique.Scientific reports · 2026Article
- Recent Advances in Diagnosing and Treating Post-Prostatectomy Urinary Incontinence.Annals of surgical oncology · 2024Review
- Initial Experience with an Absorbable Urologic Scaffold to Mitigate Early Urinary Incontinence following Radical Prostatectomy: A Report of 2 Cases.Urologia internationalis · 2024Article
- Latest Evidence on Post-Prostatectomy Urinary Incontinence.Journal of clinical medicine · 2023Review
- Relationship communication and the course of psychological outcomes among couples coping with localised prostate cancer.European journal of cancer care · 2021Article
- How radical prostatectomy procedures have changed over the last 10 years in Italy: a comparative analysis based on more than 1500 patients participating in the MIRROR-SIU/LUNA and the Pros-IT CNR study.World journal of urology · 2021Article
- Sexual well-being and diurnal cortisol after prostate cancer treatment.Journal of health psychology · 2020Article
- Relationship intimacy processes during treatment for couple-focused interventions for prostate cancer patients and their spouses.Journal of psychosocial oncology research and practice · 2019Article
- Long-Term Clinical Outcomes of Radical Prostatectomy versus Watchful Waiting in Localized Prostate Cancer Patients: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2019Review
- Interpersonal processes and intimacy among men with localized prostate cancer and their partners.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2018Article
- The Impact of Central Obesity on Storage Luts and Urinary Incontinence After Prostatic Surgery.Current urology reports · 2016Review
- Holding back, intimacy, and psychological and relationship outcomes among couples coping with prostate cancer.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2015Article
- The primary health care physician and the cancer patient: tips and strategies for managing sexual health.Translational andrology and urology · 2015Review
- Surgery and hormonal treatment for prostate cancer and sexual function.Translational andrology and urology · 2015Review
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAfter long term disease free follow up (FUp) patients reconsider quality of life (QOL) outcomes. Aim of this study is assess QoL in prostate cancer patients who are disease-free at least 5 years after radical prostatectomy (RP).
methods367 patients treated with RP for clinically localized pCa, without biochemical failure (PSA <or= 0.2 ng/mL) at the follow up >or= 5 years were recruited.Urinary (UF) and Sexual Function (SF), Urinary (UB) and Sexual Bother (SB) were assessed by using UCLA-PCI questionnaire. UF, UB, SF and SB were analyzed according to: treatment timing (age at time of RP, FUp duration, age at time of FUp), tumor characteristics (preoperative PSA, TNM stage, pathological Gleason score), nerve sparing (NS) procedure, and hormonal treatment (HT).We calculated the differences between 93 NS-RP without HT (group A) and 274 non-NS-RP or NS-RP with HT (group B). We evaluated the correlation between function and bother in group A according to follow-up duration.
resultsTime since prostatectomy had a negative effect on SF and a positive effect SB (both p < 0.001). Elderly men at follow up experienced worse UF and SF (p = 0.02 and p < 0.001) and better SB (p < 0.001).Higher stage PCa negatively affected UB, SF, and SB (all: p <or= 0.05). NS was associated with better UB, SF and SB (all: p <or= 0.05); conversely, HT was associated with worse UF, SF and SB (all: p <or= 0.05).More than 8 years after prostatectomy SF of group A and B were similar. Group A subjects (NS-RP without HT) demonstrated worsening SF, but improved SB, suggesting dissociation of the correlation between SF and SB over time.
conclusionOlder age at follow up and higher pathological stage were associated with worse QoL outcomes after RP. The direct correlation between UF and age at follow up, with no correlation between UF and age at time of RP suggests that other issues (i.e: vascular or neurogenic disorders), subsequent to RP, are determinant on urinary incontinence. After NS-RP without HT the correlation between SF and SB is maintained for 7 years, after which function and bother appear to have divergent trajectories.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.