ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2010
Esophagogastric junction distensibility after fundoplication assessed with a novel functional luminal imaging probe.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04951739 (To Investigate the Incidence of Reflux in Patients After Per-oral Endoscopic Myotomy in Achalasia Cardia Patients), which is not on this map. Cited by 55 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
To Investigate the Incidence of Reflux in Patients After Per-oral Endoscopic Myotomy in Achalasia Cardia Patients
Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Use of the Functional Lumen Imaging Probe in Clinical Esophagology.The American journal of gastroenterology · 2020Guideline
- ACG Clinical Guidelines: Clinical Use of Esophageal Physiologic Testing.The American journal of gastroenterology · 2020Guideline
- Esophagogastric junction distensibility assessed using the functional lumen imaging probe.World journal of gastroenterology · 2017Pooled it
- Esophageal peristalsis in health and disease: mechanistic insights.Physiological reviews · 2026Review
- Functional Lumen Imaging Probe (EndoFLIP) in Upper Gastrointestinal Disorders: Current Evidence, Clinical Applications, and Future Perspectives.Diseases (Basel, Switzerland) · 2026Review
- Integrating Impedance Planimetry With the Padova Classification: A Valuable Direction for Future Refinement.Neurogastroenterology and motility · 2026Article
- Functional lumen imaging probe use in a high-volume practice: Practical and technical implications.World journal of gastrointestinal endoscopy · 2024Article
- Utilizing Esophageal Motility Tests in Diagnosing and Evaluating Gastroesophageal Reflux Disease.Diagnostics (Basel, Switzerland) · 2024Review
- Secondary peristalsis and esophagogastric junction distensibility in symptomatic post-fundoplication patients.Neurogastroenterology and motility · 2024Article
- Impedance planimetry (EndoFLIPTM) and surgical outcomes after Hill compared to Toupet fundoplication.Surgical endoscopy · 2024Article
- Fundoplication in children with esophageal atresia: preoperative workup and outcome.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2022Article
- Utility of Functional Lumen Imaging Probe in Long-Term Follow-Up of Children with Esophageal Atresia: A Single-Center Retrospective Study.Children (Basel, Switzerland) · 2022Article
- Impedance planimetry (EndoFLIP™) reveals changes in gastroesophageal junction compliance during fundoplication.Surgical endoscopy · 2022Review
- Crural closure, not fundoplication, results in a significant decrease in lower esophageal sphincter distensibility.Surgical endoscopy · 2022Article
- Devices for esophageal function testing.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2022Article
- Novel Advances in the Evaluation and Treatment of Children With Symptoms of Gastroesophageal Reflux Disease.Frontiers in pediatrics · 2022Review
- Using a standardized intra-operative endoflip protocol during fundoplication to identify factors that affect distensibility.Surgical endoscopy · 2021Article
- Utilizing functional lumen imaging probe in directing treatment for post-fundoplication dysphagia.Surgical endoscopy · 2021Article
- The Usefulness of the Measurement of Esophagogastric Junction Distensibility by EndoFLIP in the Diagnosis of Gastroesophageal Reflux Disease.Gut and liver · 2021Article
- Experience-based expert consensus on the intra-operative usage of the Endoflip impedance planimetry system.Surgical endoscopy · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveThe aim of the study was to compare the esophagogastric junction (EGJ) compliance in response to controlled distension in fundoplication (FP) patients and controls using the functional luminal imaging probe (FLIP).
backgroundFP aims to replicate normal EGJ distensibility. FLIP is a new technology that uses impedance planimetry to measure intraluminal cross-sectional area (CSA) during controlled distension.
methodsTen controls and ten FP patients were studied with high-resolution esophageal pressure topography (HREPT) and then the FLIP placed across the EGJ. Deglutitive and interdeglutitive EGJ distensibility was assessed with volume-controlled distension. The FLIP measured eight CSAs spaced 4 mm apart within a cylindrical saline-filled bag along with the corresponding intrabag pressure.
resultsThe EGJ formed an hourglass shape during distensions with the central constriction at the diaphragmatic hiatus. The distensibility of the hiatus was significantly greater during deglutitive relaxation in both subject groups, but FP patients exhibited reduced EGJ distensibility and compliance compared to controls. During the interglutitive period, the corresponding increase in intrabag pressures at larger volumes were also greater in FP patients implying a longer segment of EGJ constriction. The EGJ distensibility characteristics did not correlate with HREPT measures.
conclusionsFLIP technology was used to compare EGJ distensibility in FP patients and control subjects. The least distensible locus within the EGJ was always at the hiatus. EGJ distensibility was significantly reduced, and the length of constriction increased in FP patients. Future FLIP studies will compare patients with and without post-FP dysphagia and gas bloat, symptoms suggestive of an overly restrictive FP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.