Evidence map›Paper›PMID 19911177›Full record

ArticleImmunogenetics2009

Cattle Ly49 is polymorphic.

Melanie J Dobromylskyj, Timothy Connelley, John A Hammond, Shirley A Ellis

Abstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Recognition ofInnate immunity · 2023
    Review
  2. Two Lineages ofJournal of immunology (Baltimore, Md. : 1950) · 2020
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Melanie J DobromylskyjLivestock Infectious Disease Programme, Institute for Animal Health, Compton RG20 7NN, UK.
Timothy Connelley
John A Hammond
Shirley A Ellis
The Pirbright Institute · GBNewbury College · USRoslin Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00001410
6 · The paper itself

Abstract

Cattle are the only non-primate species to have an expanded KIR gene family. In addition they have a single Ly49 gene, thought to be monomorphic. We have identified two additional Ly49 cDNA sequences in cattle that encode molecules predicted to differ by 14 and 16 amino acids from the original sequence. All available data indicate the presence of only one Ly49 gene in cattle, thus the divergent sequences reported here may represent ancient allelic lineages, a high level of polymorphism in an ancestral gene or a previously expanded and subsequently contracted Ly49 gene family. Cattle are the only species known to have an expanded polymorphic KIR gene family and a polymorphic Ly49 gene.

Indexed as

AllelesPolymorphism, GeneticAmino Acid SequenceAnimalsCattleCloning, MolecularDNA, ComplementaryGenetic VariationMolecular Sequence DataNK Cell Lectin-Like Receptor Subfamily APhylogenySequence Analysis, DNASequence Homology, Amino AcidDNA, ComplementaryNK Cell Lectin-Like Receptor Subfamily A

Identifiers

PMID19911177
OpenAlexW2168381225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.