Evidence map›Paper›PMID 19911170›Full record

Trial reportPsychopharmacology2010

Decreases in recollective experience following acute alcohol: a dose-response study.

James A Bisby, Julie R Leitz, Celia J A Morgan, H Valerie Curran

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Psychopharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Episodic foresight is impaired following acute alcohol intoxication.Journal of psychopharmacology (Oxford, England) · 2023
    Trial
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  6. The testing effect for visual materials depends on preexisting knowledge.Journal of experimental psychology. Learning, memory, and cognition · 2023
    Article
  7. Article
  8. Frontal alpha asymmetry in alcohol-related intimate partner violence.Social cognitive and affective neuroscience · 2019
    Article
  9. Review
  10. Titrating Tipsy Targets: The Neurobiology of Low-Dose Alcohol.Trends in pharmacological sciences · 2017
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James A BisbyClinical Psychopharmacology Unit, University College London, Gower Street, London, UK. j.bisby@ucl.ac.uk
Julie R Leitz
Celia J A Morgan
H Valerie Curran

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleAcute alcohol intoxication induces a selective impairment of recognition memory associated with conscious recollection whilst recognition based on familiarity is left intact.

objectivesWe aimed to further elucidate the acute effects of alcohol on recognition memory by assessing three different doses of alcohol and examining the way in which this affected the recollection and familiarity components of recognition memory in comparison to a placebo group.

methodsA double-blind independent design was used, and participants received either alcohol (0.4, 0.6 or 0.8 g/kg) or a placebo drink. Participants encoded word pairs with depth of processing manipulated under generate and read conditions. Recognition memory was assessed and recollective awareness was examined through use of the remember-know procedure.

resultsAlcohol produced a dose-dependent reduction in recognition memory associated with recollection, evidenced by decreases in the number of correctly recognised items with 'remember' responses compared to placebo. Recognition based on a familiarity, evidenced by 'know' responses, showed no differences between groups or pattern of reduction compared to the placebo group. However, a negative correlation was found between recognition based on familiarity and levels of intoxication.

conclusionsAlcohol-induced impairments in recognition memory occur in a dose-dependent manner, specifically driven by reductions in recognition associated with conscious awareness.

Indexed as

AdultAlcoholic IntoxicationAwarenessCentral Nervous System DepressantsDose-Response Relationship, DrugDouble-Blind MethodEthanolFemaleHumansMaleMental RecallRecognition, PsychologyYoung AdultCentral Nervous System DepressantsEthanol

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.