ArticleMolecular biology of the cell2010
Mobility, microtubule nucleation and structure of microtubule-organizing centers in multinucleated hyphae of Ashbya gossypii.
Article in Molecular biology of the cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 40 citations in OpenAlex.
- Cellular anatomy of arbuscular mycorrhizal fungi.Current biology : CB · 2025Review
- Not just binary: embracing the complexity of nuclear division dynamics.Nucleus (Austin, Tex.) · 2024Review
- Analysis of Nuclear Dynamics in Nematode-Trapping Fungi Based on Fluorescent Protein Labeling.Journal of fungi (Basel, Switzerland) · 2023Article
- Courtship Ritual of Male and Female Nuclei during Fertilization in Neurospora crassa.Microbiology spectrum · 2021Article
- Sporulation inJournal of fungi (Basel, Switzerland) · 2020Review
- Analysis of the protein composition of the spindle pole body during sporulation in Ashbya gossypii.PloS one · 2019Article
- Energide-cell body as smallest unit of eukaryotic life.Annals of botany · 2018Article
- Nuclear movement in fungi.Seminars in cell & developmental biology · 2018Review
- Mechanism of nuclear movements in a multinucleated cell.Molecular biology of the cell · 2017Article
- Life as a moving fluid: fate of cytoplasmic macromolecules in dynamic fungal syncytia.Current opinion in microbiology · 2015Review
- Organization of organelles within hyphae of Ashbya gossypii revealed by electron tomography.Eukaryotic cell · 2013Article
- Nuclear repulsion enables division autonomy in a single cytoplasm.Current biology : CB · 2013Article
- Neck rotation and neck mimic docking in the noncatalytic Kar3-associated protein Vik1.The Journal of biological chemistry · 2012Article
- Heterogeneity in mitochondrial morphology and membrane potential is independent of the nuclear division cycle in multinucleate fungal cells.Eukaryotic cell · 2012Article
- Nuclear and genome dynamics in multinucleate ascomycete fungi.Current biology : CB · 2011Review
- Regulation of exit from mitosis in multinucleate Ashbya gossypii cells relies on a minimal network of genes.Molecular biology of the cell · 2011Article
- Clustering of nuclei in multinucleated hyphae is prevented by dynein-driven bidirectional nuclear movements and microtubule growth control in Ashbya gossypii.Eukaryotic cell · 2011Article
- Dynamics of multiple nuclei in Ashbya gossypii hyphae depend on the control of cytoplasmic microtubules length by Bik1, Kip2, Kip3, and not on a capture/shrinkage mechanism.Molecular biology of the cell · 2010Article
- The microtubule plus-end localization of Aspergillus dynein is important for dynein-early-endosome interaction but not for dynein ATPase activation.Journal of cell science · 2010Article
- Interaction of the Aspergillus nidulans microtubule-organizing center (MTOC) component ApsB with gamma-tubulin and evidence for a role of a subclass of peroxisomes in the formation of septal MTOCs.Eukaryotic cell · 2010Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the migration of multiple nuclei in hyphae of the filamentous fungus Ashbya gossypii. Three types of cytoplasmic microtubule (cMT)-dependent nuclear movements were characterized using live cell imaging: short-range oscillations (up to 4.5 microm/min), rotations (up to 180 degrees in 30 s), and long-range nuclear bypassing (up to 9 microm/min). These movements were superimposed on a cMT-independent mode of nuclear migration, cotransport with the cytoplasmic stream. This latter mode is sufficient to support wild-type-like hyphal growth speeds. cMT-dependent nuclear movements were led by a nuclear-associated microtubule-organizing center, the spindle pole body (SPB), which is the sole site of microtubule nucleation in A. gossypii. Analysis of A. gossypii SPBs by electron microscopy revealed an overall laminar structure similar to the budding yeast SPB but with distinct differences at the cytoplasmic side. Up to six perpendicular and tangential cMTs emanated from a more spherical outer plaque. The perpendicular and tangential cMTs most likely correspond to short, often cortex-associated cMTs and to long, hyphal growth-axis-oriented cMTs, respectively, seen by in vivo imaging. Each SPB nucleates its own array of cMTs, and the lack of overlapping cMT arrays between neighboring nuclei explains the autonomous nuclear oscillations and bypassing observed in A. gossypii hyphae.
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