ArticleAmerican journal of public health2010
Childhood cognition and risk factors for cardiovascular disease in midadulthood: the 1958 British Birth Cohort Study.
Article in American journal of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Updating the Evidence on the Association between Serum Cholesterol and Risk of Late-Life Dementia: Review and Meta-Analysis.Journal of Alzheimer's disease : JAD · 2017Pooled it
- Cognitive function in childhood and cardiovascular disease risk factors up to 6 decades later: Pooled data from two birth cohort studies.medRxiv : the preprint server for health sciences · 2026Article
- Early-life influences on the risk for later-life Alzheimer's and non-Alzheimer's dementia: A nearly full life course prospective cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- The mediating pathways between parental separation in childhood and offspring hypertension at midlife.Scientific reports · 2022Article
- Associations Between Blood Pressure and Arterial Stiffness With Cognition: Neuroaggression or Neuroselection?Journal of the American Heart Association · 2018Article
- Association of Early-Life Factors With Life-Course Trajectories of Resting Heart Rate: More Than 6 Decades of Follow-up.JAMA pediatrics · 2018Article
- Is mid-life social participation associated with cognitive function at age 50? Results from the British National Child Development Study (NCDS).BMC psychology · 2016Article
- Absence of Association between Behavior Problems in Childhood and Hypertension in Midlife.PloS one · 2016Article
- Economic gradients in early child neurodevelopment: a multi-country study.Social science & medicine (1982) · 2013Article
- Article
- Dementia and Alzheimer's disease: a new direction.The 2010 Jay L. Foster Memorial Lecture.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2011Article
- Association between attention-deficit/hyperactivity disorder symptoms and obesity and hypertension in early adulthood: a population-based study.International journal of obesity (2005) · 2011Article
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Authors and funding
3 authors.
Funding
Abstract
objectivesWe sought to establish whether associations between childhood cognition and risk factors for cardiovascular disease in adulthood are explained by common causes, or adult social position or health behavior.
methodsWe analyzed associations between cognition at age 11 and cardiovascular disease risk factors at age 45 in the 1958 British birth cohort (n=9377), with and without adjustment for covariates.
resultsGeneral ability was inversely associated with systolic and diastolic blood pressure, glycosylated hemoglobin, triglycerides (in women), body mass index, and waist circumference. Systolic blood pressure decreased by 0.47 mm Hg (95% confidence interval [CI]=-0.90, -0.05) for a 1-standard-deviation increase in ability. Separate adjustment for social class at birth, education level by adulthood, adult social class, and health behaviors reduced the associations respectively by 14% to 34%, 36% to 50%, 14% to 36%, and 24% to 73%. Full adjustment reduced associations between ability and risk factors at age 45 years by 43% to 92%, abolishing all associations.
conclusionsIncrements across the distribution of childhood cognition are associated with improvements in cardiovascular risk profile in midlife, with associations primarily mediated through adult health behavior and social destinations.
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