Evidence map›Paper›PMID 19909536›Full record

ArticleJournal of the International Society of Sports Nutrition2009

The effects of four weeks of creatine supplementation and high-intensity interval training on cardiorespiratory fitness: a randomized controlled trial.

Jennifer L Graef, Abbie E Smith, Kristina L Kendall, David H Fukuda, Jordan R Moon, Travis W Beck, Joel T Cramer, Jeffrey R Stout

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the International Society of Sports Nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 48 citations in OpenAlex.

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  15. Augmentation of Creatine in the Heart.Mini reviews in medicinal chemistry · 2016
    Review
  16. Article
  17. Creatine supplementation with specific view to exercise/sports performance: an update.Journal of the International Society of Sports Nutrition · 2012
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jennifer L Graef *Department of Health and Exercise Science, University of Oklahoma, Huston Huffman Center, 1401 Asp Avenue, Norman, OK 73019, USA.
Abbie E Smith *Department of Health and Exercise Science, University of Oklahoma, Huston Huffman Center, 1401 Asp Avenue, Norman, OK 73019, USA.
Kristina L Kendall *Department of Health and Exercise Science, University of Oklahoma, Huston Huffman Center, 1401 Asp Avenue, Norman, OK 73019, USA.
David H Fukuda *Department of Health and Exercise Science, University of Oklahoma, Huston Huffman Center, 1401 Asp Avenue, Norman, OK 73019, USA.
Jordan R Moon *Department of Health and Exercise Science, University of Oklahoma, Huston Huffman Center, 1401 Asp Avenue, Norman, OK 73019, USA.
Travis W Beck *Department of Health and Exercise Science, University of Oklahoma, Huston Huffman Center, 1401 Asp Avenue, Norman, OK 73019, USA.
Joel T Cramer *Department of Health and Exercise Science, University of Oklahoma, Huston Huffman Center, 1401 Asp Avenue, Norman, OK 73019, USA.
Jeffrey R Stout *Department of Health and Exercise Science, University of Oklahoma, Huston Huffman Center, 1401 Asp Avenue, Norman, OK 73019, USA.
University of Oklahoma · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-intensity interval training has been shown to be a time-efficient way to induce physiological adaptations similar to those of traditional endurance training. Creatine supplementation may enhance high-intensity interval training, leading to even greater physiological adaptations. The purpose of this study was to determine the effects of high-intensity interval training (HIIT) and creatine supplementation on cardiorespiratory fitness and endurance performance (maximal oxygen consumption (VO2PEAK), time-to-exhaustion (VO2PEAKTTE), ventilatory threshold (VT), and total work done (TWD)) in college-aged men.

methodsForty-three recreationally active men completed a graded exercise test to determine VO2PEAK, VO2PEAKTTE, and VT. In addition, participants completed a time to exhaustion (TTE) ride at 110% of the maximum workload reached during the graded exercise test to determine TWD (TTE (sec) x W = J). Following testing, participants were randomly assigned to one of three groups: creatine (creatine citrate) (Cr; n = 16), placebo (PL; n = 17), or control (n = 10) groups. The Cr and PL groups completed four weeks of HIIT prior to post-testing.

resultsSignificant improvements in VO2PEAK and VO2PEAKTTE occurred in both training groups. Only the Cr group significantly improved VT (16% vs. 10% improvement in PL). No changes occurred in TWD in any group.

conclusionIn conclusion, HIIT is an effective and time-efficient way to improve maximal endurance performance. The addition of Cr improved VT, but did not increase TWD. Therefore, 10 g of Cr per day for five days per week for four weeks does not seem to further augment maximal oxygen consumption, greater than HIIT alone; however, Cr supplementation may improve submaximal exercise performance.

Identifiers

PMID19909536
PMCPMC2780977
OpenAlexW2106251975

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.