ArticleThe international journal of cardiovascular imaging2010
Signal density of left ventricular myocardial segments and impact of beam hardening artifact: implications for myocardial perfusion assessment by multidetector CT coronary angiography.
Article in The international journal of cardiovascular imaging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 76 citations in OpenAlex.
- Effect of contrast material injection protocol on first-pass myocardial perfusion assessed by dual-energy dual-layer computed tomography.Quantitative imaging in medicine and surgery · 2022Article
- Computed tomography calls out nuclear imaging in its field: It doesn't matter how you are searching but what you are looking for.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- CT Role in the Assessment of Existence of Breast Cancerous Cells.Journal of biomedical physics & engineering · 2020Article
- Personalized computational modeling of left atrial geometry and transmural myofiber architecture.Medical image analysis · 2018Article
- Chest pain CT in the emergency department: Watch out for the myocardium.European journal of radiology open · 2018Article
- Myocardial computed tomography perfusion.Cardiovascular diagnosis and therapy · 2017Review
- Myocardial ischemia testing with computed tomography: emerging strategies.Cardiovascular diagnosis and therapy · 2017Review
- Geographic and demographic variabilities of quantitative parameters in stress myocardial computed tomography perfusion.The Korean journal of internal medicine · 2017Article
- Temporal averaging for analysis of four-dimensional whole-heart computed tomography perfusion of the myocardium: proof-of-concept study.The international journal of cardiovascular imaging · 2017Article
- Quantitative evaluation of beam-hardening artefact correction in dual-energy CT myocardial perfusion imaging.European radiology · 2016Article
- Update on Computed Tomography Myocardial Perfusion Imaging.Current cardiovascular imaging reports · 2016Article
- Development and validation of a segmentation-free polyenergetic algorithm for dynamic perfusion computed tomography.Journal of medical imaging (Bellingham, Wash.) · 2016Article
- Acute coronary syndrome: evaluation of detection capability using non-electrocardiogram-gated parenchymal phase CT imaging.Japanese journal of radiology · 2016Article
- Beam hardening artifact reduction using dual energy computed tomography: implications for myocardial perfusion studies.Cardiovascular diagnosis and therapy · 2015Article
- Noninvasive physiologic assessment of coronary stenoses using cardiac CT.BioMed research international · 2015Review
- Role of non-electrocardiogram-gated contrast-enhanced computed tomography in the diagnosis of acute coronary syndrome.Heart and vessels · 2015Article
- Article
- Myocardial perfusion imaging with cardiac computed tomography: state of the art.Journal of cardiovascular translational research · 2013Review
- Value of cardiac 320-multidetector computed tomography and cardiac magnetic resonance imaging for assessment of myocardial perfusion defects in patients with known chronic ischemic heart disease.The international journal of cardiovascular imaging · 2013Article
- Myocardial density analysis utilizing automated myocardial defect analysis software on resting 320-detector MDCT.The international journal of cardiovascular imaging · 2013Article
Corrections and comments
- Commented on by
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledWe sought to explore the normal myocardial signal density (SD) levels during multidetector computed tomography coronary angiography (MDCT-CA) acquisitions and evaluated the impact of beam hardening artifacts.
backgroundSince myocardial perfusion by MDCT is based on the myocardial signal density (SD), it is pivotal to determine the normal values of myocardial SD and to identify potential mechanisms of misinterpretation of perfusion defects. In routine MDCT acquisitions, we commonly visualize a considerable SD drop at the posterobasal wall resembling perfusion defects, being attributed to beam hardening artifacts. Consecutive asymptomatic patients without history of coronary artery disease (CAD) and low probability of CAD who were referred for MDCT evaluation at our institution due to inconclusive or discordant functional tests constituted the study population. Perfusion defects were defined as a myocardial segment having a SD two standard deviations below the average myocardial SD for the 16 left ventricular American Heart Association (AHA) segments. Thirty six asymptomatic patients constituted the study population. Myocardial SD was evaluated in 576 American Heart Association (AHA) segments and 36 posterobasal segments. The mean myocardial SD at the posterobasal segment was 53.5 +/- 35.1 HU, whereas the mean myocardial SD at the basal, mid and apical myocardium was 97.4 +/- 17.3, with significant differences (p < 0.001) between posterobasal and all AHA segments. Posterobasal "perfusion defects" were identified in 26 (72%) patients. The only variable associated to the presence of posterobasal SD deficit was the heart rate (61.8 +/- 6.2 bpm vs. 56.3 +/- 8.1 bpm, p = 0.04), whereas body mass index, blood SD of the left and right ventricles, contrast-to-noise ratio, and the extent of atherosclerosis were not related to the presence of "perfusion defects". In an asymptomatic population with no history of coronary artery disease, a myocardial signal density deficit mimicking a perfusion defect is a common finding in the posterobasal wall and is not related to body mass index or scan quality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.