ArticleDevelopment genes and evolution2009
Functional analysis of Ultrabithorax in the silkworm, Bombyx mori, using RNAi.
Article in Development genes and evolution, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 56 citations in OpenAlex.
- Egg Microinjection for the SilkwormBio-protocol · 2025Article
- Comparative Analysis of Transcriptome Data of Wings from Different Developmental Stages of theInternational journal of molecular sciences · 2025Article
- CRISPR-Cas13-mediated RNA editing in the silkwormZoological research · 2024Article
- Upf2-Mediated Nonsense-Mediated Degradation Pathway Involved in Genetic Compensation ofInsects · 2024Article
- Article
- Lepidopteran prolegs are novel traits, not leg homologs.Science advances · 2023Article
- Overexpression ofInternational journal of molecular sciences · 2023Article
- Flight or protection: the genesProceedings. Biological sciences · 2022Article
- RNA Interference Method for Gene Function Analysis in the Japanese Rhinoceros BeetleBio-protocol · 2022Article
- Targeting genes involved in nucleopolyhedrovirus DNA multiplication through RNA interference technology to induce resistance against the virus in silkworms.Molecular biology reports · 2020Article
- Ultrabithorax and abdominal-A specify the abdominal appendage in a dosage-dependent manner in silkworm, Bombyx mori.Heredity · 2017Article
- Article
- Review
- Regulation of Silk Genes by Hox and Homeodomain Proteins in the Terminal Differentiated Silk Gland of the Silkworm Bombyx mori.Journal of developmental biology · 2016Review
- The expression profile and promoter analysis of ultraspiracle gene in the silkworm Bombyx mori.Molecular biology reports · 2014Article
- Effects of RNAi-mediated knockdown of histone methyltransferases on the sex-specific mRNA expression of Imp in the silkworm Bombyx mori.International journal of molecular sciences · 2014Article
- Embryonic thermosensitive TRPA1 determines transgenerational diapause phenotype of the silkworm, Bombyx mori.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Article
- Targeting the diuretic hormone receptor to control the cotton leafworm, Spodoptera littoralis.Journal of insect science (Online) · 2014Article
- Antennapedia is involved in the development of thoracic legs and segmentation in the silkworm, Bombyx mori.Heredity · 2013Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The formation of abdominal appendages in insects is suppressed by the Hox genes Ultrabithorax (Ubx) and abdominal-A (abd-A), but mechanisms of the suppression can differ among species. As the function of Ubx and abd-A has been described in only a few species, more data from various insects are necessary to elucidate the evolutionary transition of regulation on abdominal appendages. We examined the function of Ubx in the silkworm Bombyx mori (Bm-Ubx) by embryonic RNA interference (RNAi). This is the first case in which functional analysis for Ubx is performed in lepidopteran insects. Larvae treated with Bm-Ubx dsRNA displayed an additional pair of thoracic leg-like protuberances in A1, whereas the other abdominal segments had no transformation. Our results suggest that Bm-Ubx is a suppressor of leg development in A1.
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