Evidence map›Paper›PMID 19908056›Full record

ArticleRadiation and environmental biophysics2010

Use of the individual data of the A-bomb survivors for biologically based cancer models.

Wolfgang F Heidenreich, H M Cullings

Abstract read
PubMed Publisher
In one paragraph

Article in Radiation and environmental biophysics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wolfgang F HeidenreichHelmholtz Zentrum München German Research Center for Environmental Health (GmbH), Institute for Radiation Protection, 85764, Neuherberg, Germany. heidenreich@helmholtz-muenchen.de
H M Cullings
Helmholtz Zentrum München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All recent analyses of the data on solid cancer incidence of the atomic bomb survivors are corrected for migration and random dose errors. In the usual treatment with grouped data and regression calibration, the calibration of doses depends on the used dose response. For solid cancers, it usually is linear. Here, an individual likelihood is presented which works without further adjustment for all dose responses. When the same assumptions are made as in the usual Poisson regression, equivalent results are obtained. But, the individual likelihood has the potential to use more detailed models for dose errors and to estimate non-linear dose responses without recalibration. As an example for the potential of the individual data set for the analysis of risk at low doses, signals for a saturating bystander effect are investigated.

Indexed as

Models, BiologicalModels, StatisticalNuclear WeaponsDose-Response Relationship, RadiationFemaleHumansLikelihood FunctionsMaleNeoplasms, Radiation-InducedPoisson DistributionRadiation DosageRegression AnalysisReproducibility of ResultsRiskSurvivorsUncertainty

Identifiers

PMID19908056
OpenAlexW2081559674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.