Evidence map›Paper›PMID 19907709›Full record

ArticleCommunicative & integrative biology2009

How do animal mitochondria tolerate water stress?

Michael A Menze, Steven C Hand

Open access · goldAbstract read
In one paragraph

Article in Communicative & integrative biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Gene expression, metabolic regulation and stress tolerance during diapause.Cellular and molecular life sciences : CMLS · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael A MenzeDivision of Cellular, Developmental and Integrative Biology, Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA. menze@lsu.edu
Steven C Hand
Louisiana State University · US

Funding

Heptocellular Response to CryopreservationR01DK046270 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI TONER, MEHMET · 1999 to 2011
$3.4M
NIDDK NIH HHS R01 DK046270
6 · The paper itself

Abstract

The vast majority of animal species do not tolerate severe water stress, but the encysted embryo of the brine shrimp Artemia franciscana is an exceptionally useful organism to investigate physiological mechanisms for enduring extreme environmental insults. Any substantial reduction in cellular water poses a threat to survival. Nevertheless anhydrobiotic animals survive virtually complete loss of cellular water. The mechanisms that govern "life without water" (anhydrobiosis) are still not well understood. With certain exceptions, it seems that a recurring strategy for tolerating severe water loss involves the accumulation of both low molecular weight solutes (e.g., trehalose or other polyol) and highly hydrophilic macromolecules such as late embryogenesis abundant (LEA) proteins, which were first described about 20 years ago in plant seeds. New studies show that LEA proteins found in animals not only protect proteins in the cytosol during desiccation, but also confer resistance to water stress, including freeze tolerance, to the mitochondrion.

Indexed as

dryingfreezinglate embryogenesis abundantmitochondriastress tolerancetargeting sequence

Identifiers

PMID19907709
PMCPMC2775242
OpenAlexW2139045383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.