ArticleProceedings of the National Academy of Sciences of the United States of America2009
Neural correlates of behavior in the moth Manduca sexta in response to complex odors.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed.
- Rabbit neonates and human adults perceive a blending 6-component odor mixture in a comparable manner.PloS one · 2013Trial
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- Neuron synchronization analyzed through spatial-temporal attention.Frontiers in computational neuroscience · 2025Article
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- Variation in the ratio of compounds in a plant volatile blend during transmission by wind.Scientific reports · 2022Article
- Invariant odor recognition with ON-OFF neural ensembles.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Functional conservation of Anopheline linalool receptors through 100 million years of evolution.Chemical senses · 2022Article
- Floral Scent Evolution in the GenusPlants (Basel, Switzerland) · 2021Article
- ABiology open · 2021Article
- Multisensory interactions regulate feeding behavior inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- A Rare Stinkhorn FungusMycobiology · 2021Article
- Leaf Induction Impacts Behavior and Performance of a Pollinating Herbivore.Frontiers in plant science · 2021Article
- Insect pectinate antennae maximize odor capture efficiency at intermediate flight speeds.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- What makes a volatile organic compound a reliable indicator of insect herbivory?Plant, cell & environment · 2019Article
- Controlling and measuring dynamic odorant stimuli in the laboratory.The Journal of experimental biology · 2019Article
- Development of a Female-Targeted Lure for the Box Tree Moth Cydalima perspectalis (Lepidoptera: Crambidae): a Preliminary Report.Journal of chemical ecology · 2019Article
- Mutagenesis of odorant coreceptorProceedings of the National Academy of Sciences of the United States of America · 2019Article
- An unbiased approach elucidates variation in (Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Fuelling on the wing: sensory ecology of hawkmoth foraging.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Review
- Food-derived volatiles enhance consumption inThe Journal of experimental biology · 2019Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors.
Funding
Abstract
With Manduca sexta as a model system, we analyzed how natural odor mixtures that are most effective in eliciting flight and foraging behaviors are encoded in the primary olfactory center in the brain, the antennal lobe. We used gas chromatography coupled with multiunit neural-ensemble recording to identify key odorants from flowers of two important nectar resources, the desert plants Datura wrightii and Agave palmeri, that elicited responses from individual antennal-lobe neurons. Neural-ensemble responses to the A. palmeri floral scent, comprising >60 odorants, could be reproduced by stimulation with a mixture of six of its constituents that had behavioral effectiveness equivalent to that of the complete scent. Likewise, a mixture of three floral volatiles from D. wrightii elicited normal flight and feeding behaviors. By recording responses of neural ensembles to mixtures of varying behavioral effectiveness, we analyzed the coding of behaviorally "meaningful" odors. We considered four possible ensemble-coding mechanisms--mean firing rate, mean instantaneous firing rate, pattern of synchronous ensemble firing, and total net synchrony of firing--and found that mean firing rate and the pattern of ensemble synchrony were best correlated with behavior (R = 41% and 43%, respectively). Stepwise regression analysis showed that net synchrony and mean instantaneous firing rate contributed little to the variation in the behavioral results. We conclude that a combination of mean-rate coding and synchrony of firing of antennal-lobe neurons underlies generalization among related, behaviorally effective floral mixtures while maintaining sufficient contrast for discrimination of distinct scents.
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