Evidence map›Paper›PMID 19906917›Full record

ReviewJournal of virology2010

Papillomavirus prophylactic vaccines: established successes, new approaches.

M Saveria Campo, Richard B S Roden

Abstract readReview
In one paragraph

Review in Journal of virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. The contribution of bovines to human health against viral infections.Environmental science and pollution research international · 2021
    Review
  2. Article
  3. Article
  4. Viral Oncology: Molecular Biology and Pathogenesis.Journal of clinical medicine · 2017
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Immunologic treatments for precancerous lesions and uterine cervical cancer.Journal of experimental & clinical cancer research : CR · 2014
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Emerging human papillomavirus vaccines.Expert opinion on emerging drugs · 2012
    Review
  16. Basics of tumor development and importance of human papilloma virus (HPV) for head and neck cancer.GMS current topics in otorhinolaryngology, head and neck surgery · 2012
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M Saveria CampoDivision of Pathological Sciences, Institute of Comparative Medicine, Garscube Campus, University of Glasgow, Glasgow G61 1QH, United Kingdom. s.campo@vet.gla.ac.uk
Richard B S Roden

Funding

Treatment of HIV- and HIV+ Patients with HPV16+ CIN2/3 Using pNGLV4a-hCRTE6E7L2 DNA vaccine administered intramuscularly via electroporationP50CA098252 · NCI · JOHNS HOPKINS UNIVERSITY · PI Richard Bruce Roden · 2003 to 2026
$53.5M
Mechanisms of Papillomavirus NeutralizationR01CA118790 · NCI · JOHNS HOPKINS UNIVERSITY · PI RODEN, RICHARD BRUCE · 2007 to 2018
$2.9M
A Phase I Study to Evaluate the Safety and Immunogenicity of HPV 16 L2 11-200R01CA133749 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HUH, WARNER KING · 2008 to 2012
$1.4M
Cancer Research UKNCI NIH HHS P50 CA098252NCI NIH HHS R01 CA118790NCI NIH HHS R01 CA133749
6 · The paper itself

Abstract

Vaccines against the human papillomaviruses (HPVs) most frequently associated with cancer of the cervix are now available. These prophylactic vaccines, based on virus-like particles (VLPs), are extremely effective, providing protection from infection in almost 100% of cases. However, the vaccines present some limitations: they are effective primarily against the HPV type present in the vaccine, are expensive to produce, and need a cold chain. Vaccines based on the minor capsid protein L2 have been very successful in animal models and have been shown to provide a good level of protection against different papillomavirus types. The potential of L2-based vaccines to protect against many types of HPVs is discussed.

Indexed as

AlphapapillomavirusAnimalsHuman Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18HumansMicroscopy, ElectronPapillomavirus InfectionsPapillomavirus VaccinesHuman Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18Papillomavirus Vaccines

Identifiers

PMID19906917
PMCPMC2812340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.