Evidence map›Paper›PMID 19906819›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2010

Prolongevity effects of an oregano and cranberry extract are diet dependent in the Mexican fruit fly (Anastrepha ludens).

Sige Zou, James R Carey, Pablo Liedo, Donald K Ingram, Binbing Yu, Reza Ghaedian

Abstract readComparative Study
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The impact of low-protein high-carbohydrate diets on aging and lifespan.Cellular and molecular life sciences : CMLS · 2016
    Review
  6. Article
  7. Nutraceuticals for geriatrics.Journal of traditional and complementary medicine · 2015
    Review
  8. Cranberry interacts with dietary macronutrients to promote healthy aging in Drosophila.The journals of gerontology. Series A, Biological sciences and medical sciences · 2014
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Effects of long-term cranberry supplementation on endocrine pancreas in aging rats.The journals of gerontology. Series A, Biological sciences and medical sciences · 2011
    Article
  18. Nectarine promotes longevity in Drosophila melanogaster.Free radical biology & medicine · 2011
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sige ZouFunctional Genomics Unit, Laboratory of Experimental Gerontology, National Institute on Aging, 251 Bayview Boulevard, Baltimore, MD 21224, USA. zous@grc.nia.nih.gov
James R Carey
Pablo Liedo
Donald K Ingram
Binbing Yu
Reza Ghaedian

Funding

TRAJECTORIES OF MORTALITY IN CAENORHABDITIS ELEGANSP01AG008761 · NIA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ROACH, DEBORAH A · 1990 to 2008
$17.5M
THE MATHEMATICAL DEMOGRAPHY OF BIODEMOGRAPHYP01AG022500 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI CAREY, JAMES R. · 2003 to 2010
$8.1M
Functional Genomic Study of Aging and Aging InterventionsZIAAG000365 · NIA · NATIONAL INSTITUTE ON AGING · PI ZOU, SIGE · 2009 to 2015
$3.7M
Evaluation of biomarkers and screening tests in the disease diagnosisZICAG001100 · NIA · NATIONAL INSTITUTE ON AGING · PI YU, BINBING · 2009 to 2012
$1.9M
The risk of dementia, disease progression and its impact on survivalZICAG001120 · NIA · NATIONAL INSTITUTE ON AGING · PI YU, BINBING · 2009 to 2010
$491k
Intramural NIH HHSNIA NIH HHS P01-AG022500-01NIA NIH HHS P01-AG08761-10
6 · The paper itself

Abstract

Botanicals have numerous health benefits. Here, we used the Mexican fruit fly to screen 14 compounds and botanicals for their prolongevity effects and found an oregano and cranberry mixture (OC) improved survival. We then evaluated prolongevity effects of OC within the context of diet composition. Individual flies were fed 0%, 1%, or 2% OC in one of the three diets containing sugar and yeast extract (SY) at a ratio of 3:1, 9:1, or 24:1. We found that prolongevity effects of OC depended upon dose, gender, and diet composition. The greatest increase in longevity was observed in females fed the SY24:1 diet with 2% OC compared to the non-supplemented diet. OC did not reduce egg laying and, hence, did not compromise fecundity under any dietary condition tested here. This study reveals the prolongevity effects of OC and supports the emerging view that benefits of botanicals on aging depend on diet composition and gender.

Indexed as

OriganumVaccinium macrocarponAnimalsAppetitive BehaviorDietFemaleLongevityMalePlant ExtractsTephritidaePlant Extracts

Identifiers

PMID19906819
PMCPMC2796885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.