ReviewCurrent biology : CB2009
The shape of motile cells.
Review in Current biology : CB, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
117 citing papers in PubMed.
- Data modeling the interplay between single-cell shape, single-cell protein expression, and tissue state.Cell reports methods · 2026Article
- In situ detection of dead cells from live cells via a DC plus low frequency AC resistive pulse sensor.Biomedical microdevices · 2026Article
- Effect of Extracellular Matrix Derived from Porcine Tissue on Stemness of Porcine Spermatogonial Stem Cells.International journal of molecular sciences · 2025Article
- Cell-TIMP: Cellular Trajectory Inference Based on Morphological Parameters.Nano letters · 2025Article
- Quantification of bacterial shape using moment invariants enables distinguishing populations during cellular plasmolysis.MethodsX · 2024Article
- The Plasma Membrane and Mechanoregulation in Cells.ACS omega · 2024Review
- Generative modeling of biological shapes and images using a probabilisticbioRxiv : the preprint server for biology · 2024Article
- Morphomigrational description as a new approach connecting cell's migration with its morphology.Scientific reports · 2023Article
- Adhesion to the Brain Endothelium Selects Breast Cancer Cells with Brain Metastasis Potential.International journal of molecular sciences · 2023Article
- Microvillar Cartography: A Super-Resolution Single-Molecule Imaging Method to Map the Positions of Membrane Proteins with Respect to Cellular Surface Topography.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Emerging evidence on Monkeypox: resurgence, global burden, molecular insights, genomics and possible management.Frontiers in cellular and infection microbiology · 2023Review
- A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022Article
- A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis.Angewandte Chemie (International ed. in English) · 2022Article
- Binding Networks Identify Targetable Protein Pockets for Mechanism-Based Drug Design.International journal of molecular sciences · 2022Article
- FVIII regulates the molecular profile of endothelial cells: functional impact on the blood barrier and macrophage behavior.Cellular and molecular life sciences : CMLS · 2022Article
- Interplay among cell migration, shaping, and traction force on a matrix with cell-scale stiffness heterogeneity.Biophysics and physicobiology · 2022Article
- Self-organization in amoeboid motility.Frontiers in cell and developmental biology · 2022Review
- MAGI1 localizes to mature focal adhesion and modulates endothelial cell adhesion, migration and angiogenesis.Cell adhesion & migration · 2021Article
- Article
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57 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Motile cells - fan-like keratocytes, hand-shaped nerve growth cones, polygonal fibroblasts, to name but a few - come in different shapes and sizes. We discuss the origins of this diversity as well as what shape tells us about the physics and biochemistry underlying cell movement. We start with geometric rules describing cell-edge kinetics that govern cell shape, followed by a discussion of the underlying biophysics; we consider actin treadmilling, actin-myosin contraction, cell-membrane deformations, adhesion, and the complex interactions between these modules, as well as their regulation by microtubules and Rho GTPases. Focusing on several different cell types, including keratocytes and fibroblasts, we discuss how dynamic cell morphology emerges from the interplay between the different motility modules and the environment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.