Evidence map›Paper›PMID 19904979›Full record

ArticleNano letters2010

Photo-targeted nanoparticles.

Tal Dvir, Matthew R Banghart, Brian P Timko, Robert Langer, Daniel S Kohane

Abstract read
In one paragraph

Article in Nano letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 127 citations in OpenAlex.

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  14. Autonomous bacterial nanoswimmers target cancer.Journal of controlled release : official journal of the Controlled Release Society · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tal DvirDepartment of Chemical Engineering, Massachusetts Institute of Technology, 45 Carleton Street, Cambridge, MA 02142, USA.
Matthew R Banghart
Brian P Timko
Robert Langer
Daniel S Kohane
Boston Children's Hospital · USHarvard University · USMassachusetts Institute of Technology · US

Funding

Prolonged Duration Local AnesthesiaR01GM073626 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI KOHANE, DANIEL S · 2006 to 2018
$4.7M
NIGMS NIH HHS GM073626NIGMS NIH HHS R01 GM073626
6 · The paper itself

Abstract

We report a novel and simple proof-of-concept of a nanoparticulate system that targets any tissue selectively upon illumination. Nanoparticles were covalently functionalized with the amino acid sequence YIGSR, which adheres to the beta1 integrins present on most cell surfaces. This peptide was masked with a caging group, rendering it biologically inert. Illumination with UV light released the caging group from the YIGSR, allowing binding to cells.

Indexed as

AnimalsCells, CulturedChromatography, High Pressure LiquidHumansNanoparticlesNanotechnologyNitrobenzenesPeptidesPhotochemistryRatsRats, Sprague-DawleySpectroscopy, Fourier Transform InfraredTyrosineUltraviolet RaysnitrobenzeneNitrobenzenesPeptidesTyrosine

Identifiers

PMID19904979
PMCPMC2806491
OpenAlexW2027588503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.