Evidence map›Paper›PMID 19904666›Full record

Trial reportSubstance abuse

Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study.

Judson A Brewer, Rajita Sinha, Justin A Chen, Ravenna N Michalsen, Theresa A Babuscio, Charla Nich, Aleesha Grier, Keri L Bergquist, Deidre L Reis, Marc N Potenza and 2 more

Open access · greenAbstract readClinical Trial, Phase IRandomized Controlled Trial
In one paragraph

Trial report in Substance abuse. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 7 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 7 syntheses or guidelines pooled it, 284 citations in OpenAlex.

  1. Psychosocial interventions for stimulant use disorder.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Mindfulness-based interventions for substance use disorders.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Effect of alcohol on blood pressure.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Effects of behavioral interventions on stress reactivity in adults with substance use disorders.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
    Trial
  10. Trial
  11. Craving to Quit: A Randomized Controlled Trial of Smartphone App-Based Mindfulness Training for Smoking Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Judson A BrewerDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA. judson.brewer@yale.edu
Rajita Sinha
Justin A Chen
Ravenna N Michalsen
Theresa A Babuscio
Charla Nich
Aleesha Grier
Keri L Bergquist
Deidre L Reis
Marc N Potenza
Kathleen M Carroll
Bruce J Rounsaville
Yale University · US

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
Sex Differences in Stress Related RelapseP50DA016556 · NIDA · YALE UNIVERSITY · PI SINHA, RAJITA · 2002 to 2011
$10.4M
Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Computer-Based Training in Cognitve Behavioral TherapyR37DA015969 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2003 to 2009
$2.6M
fMRI of CBT and CM for Cocaine DependenceR01DA020908 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2005 to 2009
$1.7M
fMRI of Craving in Addictions: Gender DifferencesR01DA019039 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2005 to 2009
$1.6M
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)RL1AA017539 · NIAAA · YALE UNIVERSITY · PI POTENZA, MARC N · 2007 to 2011
$1.3M
PSYCHOTHERAPY OF SUBSTANCE USE DISORDERSK05DA000457 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2000 to 2009
$1.2M
DIAGNOSIS &TREATMENT OF SUBSTANCE USE DISORDERSK05DA000089 · NIDA · YALE UNIVERSITY · PI ROUNSAVILLE, BRUCE JAMES · 1988 to 2008
$1.0M
Sex-Specific Pathways Linking Stress and Drug AbuseK02DA017232 · NIDA · YALE UNIVERSITY · PI SINHA, RAJITA · 2004 to 2008
$635k
NIAAA NIH HHS RL1 AA017539NIDA NIH HHS K02 DA017232NIDA NIH HHS K02-DA17232NIDA NIH HHS K05 DA000089NIDA NIH HHS K05 DA000457NIDA NIH HHS K05-DA00089NIDA NIH HHS K05-DA00457NIDA NIH HHS K12 DA000167NIDA NIH HHS K12-DA00167NIDA NIH HHS P50 DA009241NIDA NIH HHS P50 DA016556NIDA NIH HHS P50-DA09241NIDA NIH HHS P50-DA16556NIDA NIH HHS R01 DA019039NIDA NIH HHS R01 DA020908NIDA NIH HHS R37 DA015969NIDA NIH HHS R37-DA15969NIDA NIH HHS T32 DA007238NIDA NIH HHS T32-DA007238
6 · The paper itself

Abstract

Stress is important in substance use disorders (SUDs). Mindfulness training (MT) has shown promise for stress-related maladies. No studies have compared MT to empirically validated treatments for SUDs. The goals of this study were to assess MT compared to cognitive behavioral therapy (CBT) in substance use and treatment acceptability, and specificity of MT compared to CBT in targeting stress reactivity. Thirty-six individuals with alcohol and/or cocaine use disorders were randomly assigned to receive group MT or CBT in an outpatient setting. Drug use was assessed weekly. After treatment, responses to personalized stress provocation were measured. Fourteen individuals completed treatment. There were no differences in treatment satisfaction or drug use between groups. The laboratory paradigm suggested reduced psychological and physiological indices of stress during provocation in MT compared to CBT. This pilot study provides evidence of the feasibility of MT in treating SUDs and suggests that MT may be efficacious in targeting stress.

Indexed as

AttentionAdultBehavior, AddictiveCognitive Behavioral TherapyFemaleGalvanic Skin ResponseHumansMaleMeditationMiddle AgedPatient CompliancePatient SatisfactionPilot ProjectsStress, PhysiologicalStress, PsychologicalSubstance-Related Disorders

Identifiers

PMID19904666
PMCPMC3045038
OpenAlexW2016734002

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.