ArticleJPEN. Journal of parenteral and enteral nutrition
Challenges to optimal enteral nutrition in a multidisciplinary pediatric intensive care unit.
Article in JPEN. Journal of parenteral and enteral nutrition. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
COntinuous vs BOlus Nasogastric Feeding in Mechanically Ventilated Pediatric Patients 2
Stage 1Evaluation of Status of Early Reached Target Enteral Nutrition in Critically Ill Children in the PICU (ERTEN in PICU) Stage 2 IFABP as Biomarker of Feeding Intolerance in Critically Ill Children in the PICU(IFABP in PICU)
Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 184 citations in OpenAlex.
- Factors that influence the provision of enteral feeding for critically ill children: a qualitative evidence synthesis.BMC nutrition · 2025Pooled it
- Gastrointestinal Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.Pediatrics · 2022Pooled it
- Chinese guidelines for the assessment and provision of nutrition support therapy in critically ill children.World journal of pediatrics : WJP · 2018Pooled it
- An integrated systematic review and meta-analysis of published randomized controlled trials evaluating nasogastric against postpyloris (nasoduodenal and nasojejunal) feeding in critically ill patients admitted in intensive care unit.European journal of clinical nutrition · 2014Pooled it
- Early Enteral Nutrition Is Associated With Improved Clinical Outcomes in Critically Ill Children: A Secondary Analysis of Nutrition Support in the Heart and Lung Failure-Pediatric Insulin Titration Trial.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020Trial
- Non-Thyroidal Illness Syndrome in Critically Ill Children: Prognostic Value and Impact of Nutritional Management.Thyroid : official journal of the American Thyroid Association · 2019Trial
- Early enteral nutrition therapy in congenital cardiac repair postoperatively: A randomized, controlled pilot study.Annals of cardiac anaesthesiaTrial
- The Interplay Between Nutrition and Microbiota and the Role of Probiotics and Symbiotics in Pediatric Infectious Diseases.Nutrients · 2025Review
- Interruptions in nutritional therapy in children with chronic diseases during the acute phase of critical illness and their effect on the administered volume.Frontiers in nutrition · 2025Article
- Trajectories of acute gastrointestinal injury grade in critically Ill children.BMC pediatrics · 2024Article
- Impact of Early Enteral Nutrition on the Hospital Stay of Pediatric Patients Undergoing Mechanical Ventilation.Journal of pediatric intensive care · 2024Article
- Measurements of enteral feeding intolerance in critically ill children: a scoping review.Frontiers in pediatrics · 2024Article
- Timing of parenteral nutrition initiation in critically ill children: a randomized clinical trial.Clinical and experimental pediatrics · 2023Article
- A Retrospective Study of Complications of Enteral Feeding in Critically Ill Children on Noninvasive Ventilation.Nutrients · 2023Article
- Impact of implementing an evidence-based definition of enteral nutrition intolerance on nutrition delivery: A prospective, cross-sectional cohort study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023Article
- Prevalence, Risk Factors and Impact of Nutrition Interruptions in Critically Ill Children.Nutrients · 2023Article
- Evaluation of nutritional status in pediatric intensive care unit patients: the results of a multicenter, prospective study in Turkey.Frontiers in pediatrics · 2023Article
- Nutritional Management of Patients with Fontan Circulation: A Potential for Improved Outcomes from Birth to Adulthood.Nutrients · 2022Review
- The Role of the Pediatric Yorkhill Malnutrition Score (PYMS), Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Malnutrition Prediction of Hospitalized Children.Children (Basel, Switzerland) · 2022Article
- Nutrition practices and outcomes in patients with pediatric acute respiratory distress syndrome.JPEN. Journal of parenteral and enteral nutrition · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveTo describe nutrient intake in critically ill children, identify risk factors associated with avoidable interruptions to enteral nutrition (EN), and highlight opportunities to improve enteral nutrient delivery in a busy tertiary pediatric intensive care unit (PICU). Design, Setting, and Measurements: Daily nutrient intake and factors responsible for avoidable interruptions to EN were recorded in patients admitted to a 29-bed medical and surgical PICU over 4 weeks. Clinical characteristics, time to reach caloric goal, and parenteral nutrition (PN) use were compared between patients with and without avoidable interruptions to EN.
resultsDaily record of nutrient intake was obtained in 117 consecutive patients (median age, 7 years). Eighty (68%) patients received EN (20% postpyloric) for a total of 381 EN days (median, 2 days). Median time to EN initiation was less than 1 day. However, EN was subsequently interrupted in 24 (30%) patients at an average of 3.7 +/- 3.1 times per patient (range, 1-13), for a total of 88 episodes accounting for 1,483 hours of EN deprivation in this cohort. Of the 88 episodes of EN interruption, 51 (58%) were deemed as avoidable. Mechanically ventilated subjects were at the highest risk of EN interruptions. Avoidable EN interruption was associated with increased reliance on PN and impaired ability to reach caloric goal.
conclusionsEN interruption is common and frequently avoidable in critically ill children. Knowledge of existing barriers to EN such as those identified in this study will allow appropriate interventions to optimize nutrition provision in the PICU.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.