Evidence map›Paper›PMID 19903479›Full record

ReviewFEBS letters2009

Systems biology from a yeast omics perspective.

Michael Snyder, Jennifer E G Gallagher

Abstract readReview
In one paragraph

Review in FEBS letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Yeast as a Model for Human Disease.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Yeast Systems Biology: The Continuing Challenge of Eukaryotic Complexity.Methods in molecular biology (Clifton, N.J.) · 2019
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Physical and genetic-interaction density reveals functional organization and informs significance cutoffs in genome-wide screens.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  14. Review
  15. Article
  16. ScreenTroll: a searchable database to compare genome-wide yeast screens.Database : the journal of biological databases and curation · 2012
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael SnyderDepartment of Genetics, Stanford University, Stanford, CA 94305, USA. mpsnyder@stanford.edu
Jennifer E G Gallagher

Funding

INSTITUTIONAL TRAINING GRANT IN GENOME SCIENCET32HG000044 · NHGRI · STANFORD UNIVERSITY · PI MICHAEL P. SNYDER · 1995 to 2026
$32.2M
Global Analysis of Transcription Regulatory NetworksR01CA077808 · NCI · YALE UNIVERSITY · PI SNYDER, MICHAEL P. · 1997 to 2009
$6.8M
NCI NIH HHS R01 CA077808NHGRI NIH HHS T32 HG000044
6 · The paper itself

Abstract

Systems biology represents a paradigm shift from the study of individual genes, proteins or other components to that of the analysis of entire pathways, cellular, developmental, or organismal processes. Large scale studies, primarily initiated in Saccharomyces cerevisiae, have allowed the identification and characterization of components on an unprecedented level. Large scale interaction, transcription factor binding and phosphorylation data have enabled the elucidation of global regulatory networks. These studies have helped provide an understanding of cellular pathways and processes at a global and systems level.

Indexed as

Gene Expression ProfilingGenomicsMetabolic Networks and PathwaysMetabolomicsPhosphorylationProtein Interaction MappingSaccharomyces cerevisiaeSystems BiologyTranscription FactorsTranscription Factors

Identifiers

PMID19903479
PMCPMC3262145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.