Evidence map›Paper›PMID 19903428›Full record

ArticleCurrent gastroenterology reports2009

Managing the risks of IBD therapy.

Cynthia H Seow, Shanika de Silva, Gilaad G Kaplan, Shane M Devlin, Subrata Ghosh, Remo Panaccione

Abstract read
PubMed Publisher
In one paragraph

Article in Current gastroenterology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Treat to Target in Inflammatory Bowel Disease.Current treatment options in gastroenterology · 2016
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cynthia H SeowUniversity of Calgary, TRW Building, Room 6D18, Calgary, Canada. cseow@ucalgary.ca
Shanika de Silva
Gilaad G Kaplan
Shane M Devlin
Subrata Ghosh
Remo Panaccione

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Successful management of the patient with inflammatory bowel disease (IBD) involves not only the induction and maintenance of remission, but also the optimization of the benefit-to-risk equation to achieve the greatest gain in quality of life. These risks range from intolerance to prescribed medications to potentially life-threatening sequelae (eg, sepsis) of immune suppression. A proper awareness of risk on the part of the physician and education of the patient can lead to early detection and institution of an appropriate management plan, including risk management and, optimally, primary prevention (eg, prophylactic vaccination). One should take the opportunity regularly to reassess the utility and efficacy of existing therapy, with the provision of ineffective therapies mandating urgent review. Overall, optimal management of the patient with IBD requires open dialogue between clinician and patient so that both are cognizant of the goals, benefits, and potential risks of therapy.

Indexed as

Anti-Bacterial AgentsAntibodies, MonoclonalAnti-Inflammatory AgentsGlucocorticoidsHumansImmunologic FactorsImmunosuppressive AgentsInflammatory Bowel DiseasesMesalamineRisk ManagementSulfasalazineAnti-Bacterial AgentsAntibodies, MonoclonalAnti-Inflammatory AgentsGlucocorticoidsImmunologic FactorsImmunosuppressive AgentsMesalamineSulfasalazine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.