Evidence map›Paper›PMID 1990274›Full record

ArticleMolecular and cellular biology1991

Nuclear and cytoplasmic location of the FER tyrosine kinase.

Q L Hao, D K Ferris, G White, N Heisterkamp, J Groffen

Open access · greenAbstract readComparative Study
In one paragraph

Article in Molecular and cellular biology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Involvement of the tyrosine kinase fer in cell adhesion.Molecular and cellular biology · 1998
    Article
  11. Article
  12. Article
  13. Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation.Proceedings of the National Academy of Sciences of the United States of America · 1992
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Q L HaoDepartment of Pathology, Childrens Hospital, Los Angeles 90027.
D K Ferris
G White
N Heisterkamp
J Groffen
Children's Hospital of Los Angeles · USNational Cancer Institute · US

Funding

OPERATIONS AND TECHNICAL SUPPORTN01CO074102 · CO · PROGRAM RESOURCES, INC. · PI COMPTON, THOMAS F · 1987 to 1998
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CHARACTERIZATION OF BCR AND ABL RELATED GENESR01CA047456 · NCI · CHILDREN'S HOSPITAL LOS ANGELES · PI GROFFEN, JOHN H · 1988 to 1999
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CHARACTERIZATION OF BCR AND ABL RELATED GENESR55CA047456 · NCI · CHILDREN'S HOSPITAL LOS ANGELES · PI GROFFEN, JOHN H · 1991 to 1991
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NCI NIH HHS CA 47456NCI NIH HHS N01-CO-74102
6 · The paper itself

Abstract

The location of the FER protein within the cell was investigated by using subcellular fractionation and immunofluorescence. FER was found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes.

Indexed as

Amino Acid SequenceAnimalsCell LineCell NucleusCytoplasmFluorescent Antibody TechniqueGenes, mycHumansMaleMolecular Sequence DataProtein-Tyrosine KinasesProto-Oncogene ProteinsSequence Homology, Nucleic AcidProtein-Tyrosine Kinasesproto-oncogene protein c-fes-fpsProto-Oncogene Proteins

Identifiers

PMID1990274
PMCPMC359807
OpenAlexW1791804531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.