ArticleLa Radiologia medica2010
Diffusion-weighted imaging in breast lesion evaluation.
Article in La Radiologia medica, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05384535 (Utility of Biparametric MRI), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Can apparent diffusion coefficient (ADC) distinguish breast cancer from benign breast findings? A meta-analysis based on 13 847 lesions.BMC cancer · 2019Pooled it
- Effect of b value and pre-admission of contrast on diagnostic accuracy of 1.5-T breast DWI: a systematic review and meta-analysis.European radiology · 2014Pooled it
- Ensemble Learning for Breast Cancer Lesion Classification: A Pilot Validation Using Correlated Spectroscopic Imaging and Diffusion-Weighted Imaging.Metabolites · 2023Article
- Article
- Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic review.Exploration of targeted anti-tumor therapy · 2022Review
- Predictive value of T2-weighted magnetic resonance imaging for the prognosis of patients with mass-type breast cancer with peritumoral edema.Oncology letters · 2020Article
- Correlation between minimum apparent diffusion coefficient values and the histological grade of breast invasive ductal carcinoma.Oncology letters · 2018Article
- Fat suppression techniques (STIR vs. SPAIR) on diffusion-weighted imaging of breast lesions at 3.0 T: preliminary experience.La Radiologia medica · 2015Article
- Nonmalignant breast lesions: ADCs of benign and high-risk subtypes assessed as false-positive at dynamic enhanced MR imaging.Radiology · 2012Article
- MRI evaluation of neoadjuvant low-dose fractionated radiotherapy with concurrent chemotherapy in patients with locally advanced breast cancer.The British journal of radiology · 2012Article
- Diffusion tensor magnetic resonance imaging of the normal breast: reproducibility of DTI-derived fractional anisotropy and apparent diffusion coefficient at 3.0 T.La Radiologia medica · 2012Article
- Apparent diffusion coefficient measurements in the differentiation between benign and malignant lesions: a systematic review.Insights into imaging · 2012Article
- MR-diffusion imaging in assessing chronic liver diseases: does a clinical role exist?La Radiologia medica · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to investigate the ability of diffusion-weighted imaging (DWI) and the apparent diffusion coefficient (ADC) in the detection and characterisation of breast lesions. MATERIALS AND
methodsFrom September 2005 to September 2007, 86 patients with breast lesions who underwent magnetic resonance imaging (MRI) in our department were included in our study. MRI was performed with a 1.5-T unit using a standard protocol including DWI sequence. For each breast lesion, the ADC value was calculated and compared with that of normal breast tissue and to the definitive pathological diagnosis. Mann-Whitney U and Kruskal-Wallis tests were used for statistical analysis.
resultsA total of 126 breast lesions were detected. Pathology results revealed 100 malignant and 26 benign lesions. Mean diameter of lesions was 26.02 mm (range 4-90 mm), including 52 lesions <or=15 mm in size. Mean ADC value of normal glandular tissue was 1.55x10(-3) mm(2)/s. Mean ADC value of malignant lesions was 0.97x10(-3) mm(2)/s. Mean ADC value for benign lesions was 1.66x10(-3) mm(2)/s. Benign lesions showed ADC values significantly higher than malignant lesions (p<0.0001).
conclusionsDWI provides reliable information to support MRI diagnosis of breast masses. ADC value appears a promising adjunctive parameter in distinguishing malignant from benign breast lesions.
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