Evidence map›Paper›PMID 19902310›Full record

Trial reportJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2010

Endoluminal fundoplication (ELF) for GERD using EsophyX: a 12-month follow-up in a single-center experience.

Alessandro Repici, Uberto Fumagalli, Alberto Malesci, Roberta Barbera, Camilla Gambaro, Riccardo Rosati

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. The evolution of TIF: transoral incisionless fundoplication.Therapeutic advances in gastroenterology · 2020
    Review
  7. Transoral incisionless fundoplication for gastro-esophageal reflux disease: Techniques and outcomes.World journal of gastrointestinal pharmacology and therapeutics · 2016
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Endoscopic fundoplication: real or fantasy?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2011
    Article
  16. Article
  17. Are incisionless fundoplication procedures a safer alternative to the laparoscopic nissen for the treatment of chronic gastroesophageal reflux disease?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2011
    Article
  18. Nissen fundoplication after failure of endoluminal fundoplication: short-term results.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2011
    Article
  19. Transoral incisionless fundoplication 2.0 procedure using EsophyX™ for gastroesophageal reflux disease.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro RepiciDepartment of Gastroenterology and Digestive Endoscopy, IRCCS Istituto Clinico Humanitas, 20089 Milan, Italy.
Uberto Fumagalli
Alberto Malesci
Roberta Barbera
Camilla Gambaro
Riccardo Rosati

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral endoscopic antireflux therapies have been proposed to reduce the need for chronic medical therapy or laparoscopic fundoplication for gastroesophageal reflux disease (GERD). Aim of this study was to evaluate the short- and mid-term clinical results of endoluminal fundoplication (ELF) with EsophyX. PATIENTS AND

methodsFrom June 2006 to April 2008, 20 patients were enrolled in the study. All the ELFs were performed under general anesthesia.

resultsThe mean duration of the procedure was 63 min (range 38-105). A median of 14 fasteners was placed. There were no major intraoperative complications. Two patients developed early complications and were treated conservatively. Four patients underwent, within the first year post-ELF, a laparoscopic fundoplication because of persistence of symptoms. One patient was lost to follow-up between 6 and 12 months. Among the other 15 patients who completed 12 months follow-up, the GERD health-related quality of life score decreased from a median of 40 to a median of 10 (p < 0.05), and seven patients were still off proton pump inhibitor. An improvement in esophageal acid exposure was recorded in 16.6% of patients, while in 66.7%, it worsened.

conclusionsELF induced improvement of GERD symptoms and patients quality of life in a subgroup of patients with a reduced need for medication. However, it did not significantly change esophageal acid exposure in these patients. The need for revisional standard laparoscopic fundoplication was high.

Indexed as

AdultAgedEndoscopy, GastrointestinalFemaleFundoplicationGastroesophageal RefluxHumansMaleMiddle AgedPostoperative Complications

Identifiers

PMID19902310

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.