ArticleJournal of visualized experiments : JoVE2009
Historical view and physiology demonstration at the NMJ of the crayfish opener muscle.
Article in Journal of visualized experiments : JoVE, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
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- Examining the effect of manganese on physiological processes: Invertebrate models.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2022Article
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- The Effect of Bacterial Endotoxin LPS on Serotonergic Modulation of Glutamatergic Synaptic Transmission.Biology · 2020Article
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- The effects of tricaine mesylate on arthropods: crayfish, crab and Drosophila.Invertebrate neuroscience : IN · 2020Article
- Physiological and Behavioral Indicators to Measure Crustacean Welfare.Animals : an open access journal from MDPI · 2019Article
- The Effects of Chloride Flux onMethods and protocols · 2019Article
- Effect of temperature change on synaptic transmission at crayfish neuromuscular junctions.Biology open · 2018Article
- Serotonin and synaptic transmission at invertebrate neuromuscular junctions.Experimental neurobiology · 2012Article
- Structure/function assessment of synapses at motor nerve terminals.Synapse (New York, N.Y.) · 2011Article
- Membrane potentials, synaptic responses, neuronal circuitry, neuromodulation and muscle histology using the crayfish: student laboratory exercises.Journal of visualized experiments : JoVE · 2011Article
- Physiological recordings of high and low output NMJs on the crayfish leg extensor muscle.Journal of visualized experiments : JoVE · 2010Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here we present some of the key important discoveries made with the opener neuromuscular (NMJ) preparation of crustaceans and illustrate that there is still much to learn from this model preparation. In understanding the history one can appreciate why even today this NMJ still offers a rich playground to address questions regarding pre- and post-synaptic function and plasticity. The viability and ease of access to the terminal for intracellular as well as extracellular electrophysiology and imaging are significant advantages. The mechanisms behind the modulation of vesicular kinetics and fusion within the high- and low-output terminals are begging for investigation. The preparation also offers a testable model system for computational assessments and manipulations to examine key variables in theoretical models of synaptic function, for example calcium dynamics during short-term facilitation. The synaptic complexity of active zone and statistical nature of quantal release is also an open area for future investigation both experimentally and computationally.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.