ArticleThe Journal of biological chemistry2010
Functional analysis of an Arabidopsis thaliana abiotic stress-inducible facilitated diffusion transporter for monosaccharides.
Article in The Journal of biological chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.
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75 citing papers in PubMed, 1 synthesis or guideline pooled it, 218 citations in OpenAlex.
- Identification of biomarker genes from multiple studies for abiotic stress in maize through machine learning.Journal of biosciences · 2024Pooled it
- Exl1 from Pectobacterium activates a jasmonate-dependent immune network in Arabidopsis thaliana.Plant molecular biology · 2026Article
- Identification and Expression Analysis of the Goji Haploid-Inducible Gene DMP.International journal of molecular sciences · 2026Article
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- Towards a Holistic View of the Orchestration Between Sugar Transporters in Cereal Crops.Plants (Basel, Switzerland) · 2026Article
- OneRosette to predict them all: single plant prompting on a visual foundation model to segment symptomatic Arabidopsis thaliana time series.Plant methods · 2025Article
- Genome-Wide Identification, Evolution, and Expression Analysis of theInternational journal of molecular sciences · 2025Article
- How vacuolar sugar transporters evolve and control cellular sugar homeostasis, organ development and crop yield.Nature plants · 2025Review
- Genome-Wide Identification of the SWEET Gene Family and Functional Analysis ofInternational journal of molecular sciences · 2025Article
- Integrative physiological, biochemical, and proteomic analysis of the leaves of two cotton genotypes under heat stress.PloS one · 2025Article
- Apple vacuolar sugar transporters regulated by MdDREB2A enhance drought resistance by promoting accumulation of soluble sugars and activating ABA signaling.Horticulture research · 2024Article
- The role of sugar transporters in the battle for carbon between plants and pathogens.Plant biotechnology journal · 2024Review
- Genomic identification and expression profiling of DMP genes in oat (Avena sativa) elucidate their responsiveness to seed aging.BMC genomics · 2024Article
- Genome-wide identification and investigation of monosaccharide transporter gene family based on their evolution and expression analysis under abiotic stress and hormone treatments in maize (Zea mays L.).BMC plant biology · 2024Article
- Genome-Wide Identification and Expression Analysis of the SWEET Gene Family inInternational journal of molecular sciences · 2023Article
- Vacuolar Sugar Transporter TMT2 Plays Crucial Roles in Germination and Seedling Development in Arabidopsis.International journal of molecular sciences · 2023Article
- Identification of genes associated with abiotic stress tolerance in sweetpotato using weighted gene co-expression network analysis.Plant direct · 2023Article
- Genome-Wide Identification of the RosePlants (Basel, Switzerland) · 2023Article
- Genome-wide identification and expression profile analysis of SWEET genes in Chinese jujube.PeerJ · 2023Article
- Article
15 more citing papers are in PubMed but not listed here.
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7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sugars play indispensable roles in biological reactions and are distributed into various tissues or organelles via transporters in plants. Under abiotic stress conditions, plants accumulate sugars as a means to increase stress tolerance. Here, we report an abiotic stress-inducible transporter for monosaccharides from Arabidopsis thaliana that is termed ESL1 (ERD six-like 1). Expression of ESL1 was induced under drought and high salinity conditions and with exogenous application of abscisic acid. Promoter analyses using beta-glucuronidase and green fluorescent protein reporters revealed that ESL1 is mainly expressed in pericycle and xylem parenchyma cells. The fluorescence of ESL1-green fluorescent protein-fused protein was detected at tonoplast in transgenic Arabidopsis plants and tobacco BY-2 cells. Furthermore, alanine-scanning mutagenesis revealed that an N-terminal LXXXLL motif in ESL1 was essential for its localization at the tonoplast. Transgenic BY-2 cells expressing mutated ESL1, which was localized at the plasma membrane, showed an uptake ability for monosaccharides. Moreover, the value of K(m) for glucose uptake activity of mutated ESL1 in the transgenic BY-2 cells was extraordinarily high, and the transport activity was independent from a proton gradient. These results indicate that ESL1 is a low affinity facilitated diffusion transporter. Finally, we detected that vacuolar invertase activity was increased under abiotic stress conditions, and the expression patterns of vacuolar invertase genes were similar to that of ESL1. Under abiotic stress conditions, ESL1 might function coordinately with the vacuolar invertase to regulate osmotic pressure by affecting the accumulation of sugar in plant cells.
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