Trial reportBMJ (Clinical research ed.)2009
ExStroke Pilot Trial of the effect of repeated instructions to improve physical activity after ischaemic stroke: a multinational randomised controlled clinical trial.
Trial report in BMJ (Clinical research ed.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00132483 (ExStroke Pilot Trial), which is not on this map. Cited by 46 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ExStroke Pilot Trial: Physical Exercise After Acute Ischaemic Stroke
Who cites it
46 citing papers in PubMed, 12 syntheses or guidelines pooled it.
- Physical Therapist Involved Physical Activity Interventions: A Systematic Review and Meta-Analysis.Journal of neurologic physical therapy : JNPT · 2026Pooled it
- Information provision for stroke survivors and their carers.The Cochrane database of systematic reviews · 2021Pooled it
- Interventions for reducing sedentary behaviour in people with stroke.The Cochrane database of systematic reviews · 2021Pooled it
- Effect and efficacy of lifestyle interventions as secondary prevention.Acta neurologica Scandinavica · 2020Pooled it
- Interventions for improving modifiable risk factor control in the secondary prevention of stroke.The Cochrane database of systematic reviews · 2018Pooled it
- A Systematic Review and Meta-Analysis on Self-Management for Improving Risk Factor Control in Stroke Patients.International journal of behavioral medicine · 2017Pooled it
- Secondary prevention lifestyle interventions initiated within 90 days after TIA or 'minor' stroke: a systematic review and meta-analysis of rehabilitation programmes.The British journal of general practice : the journal of the Royal College of General Practitioners · 2017Pooled it
- The Effectiveness of Lower-Limb Wearable Technology for Improving Activity and Participation in Adult Stroke Survivors: A Systematic Review.Journal of medical Internet research · 2016Pooled it
- Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2016Pooled it
- Interventions for preventing falls in people after stroke.The Cochrane database of systematic reviews · 2013Pooled it
- Non-pharmacological interventions for preventing secondary vascular events after stroke or transient ischemic attack.The Cochrane database of systematic reviews · 2013Pooled it
- Information provision for stroke patients and their caregivers.The Cochrane database of systematic reviews · 2012Pooled it
- Effects of structured positive feedback intervention on standing reach ability among older adults admitted to a convalescent rehabilitation ward: a small-sample pilot randomized controlled trial.European geriatric medicine · 2025Trial
- Positive-word stimuli via a smartphone application have no immediate-term effects on multi-directional reach ability in standing position: a randomized controlled trial.Annals of medicine · 2021Trial
- Peer education for secondary stroke prevention in inner-city minorities: design and methods of the prevent recurrence of all inner-city strokes through education randomized controlled trial.Contemporary clinical trials · 2012Trial
- Trial
- International randomized clinical trial, stroke inpatient rehabilitation with reinforcement of walking speed (SIRROWS), improves outcomes.Neurorehabilitation and neural repairTrial
- Effects of Sit-to-stand Exercise Instruction and Goal-setting on Reducing Sitting Time in Chronic Stroke Survivors: A Randomized Crossover Trial.Physical therapy research · 2026Article
- Trajectories of physical activity after ischaemic stroke: Exploring prediction of change.European journal of neurology · 2025Article
- WeWalk: walking with a buddy after stroke-a pilot study evaluating feasibility and acceptability of a person-centred dyadic behaviour change intervention.Pilot and feasibility studies · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate if repeated verbal instructions about physical activity to patients with ischaemic stroke could increase long term physical activity.
designMulticentre, multinational, randomised clinical trial with masked outcome assessment.
settingStroke units in Denmark, China, Poland, and Estonia.
participants314 patients with ischaemic stroke aged >or=40 years who were able to walk-157 (mean age 69.7 years) randomised to the intervention, 157 (mean age 69.4 years) in the control group.
interventionsPatients randomised to the intervention were instructed in a detailed training programme before discharge and at five follow-up visits during 24 months. Control patients had follow-up visits with the same frequency but without instructions in physical activity.
main outcome measuresPhysical activity assessed with the Physical Activity Scale for the Elderly (PASE) at each visit. Secondary outcomes were clinical events.
resultsThe estimated mean PASE scores were 69.1 in the intervention group and 64.0 in the control group (difference 5.0 (95% confidence interval -5.8 to 15.9), P=0.36. The intervention had no significant effect on mortality, recurrent stroke, myocardial infarction, or falls and fractures.
conclusionRepeated encouragement and verbal instruction in being physically active did not lead to a significant increase in physical activity measured by the PASE score. More intensive strategies seem to be needed to promote physical activity after ischaemic stroke.
trial registrationClinical Trials NCT00132483.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.