ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2010
When is electrical cortical stimulation more likely to produce afterdischarges?
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Article
- The influence of temperature and genomic variation on intracranial EEG measures in people with epilepsy.Brain communications · 2024Article
- Combining Gamma With Alpha and Beta Power Modulation for Enhanced Cortical Mapping in Patients With Focal Epilepsy.Frontiers in human neuroscience · 2020Article
- Electrical Stimulation Mapping of Brain Function: A Comparison of Subdural Electrodes and Stereo-EEG.Frontiers in human neuroscience · 2020Article
- Applying a Sensing-Enabled System for Ensuring Safe Anterior Cingulate Deep Brain Stimulation for Pain.Brain sciences · 2019Article
- Locally stable brain states predict suppression of epileptic activity by enhanced cognitive effort.NeuroImage. Clinical · 2018Article
- Impairment of consciousness induced by bilateral electrical stimulation of the frontal convexity.Epilepsy & behavior case reports · 2017Article
- Understanding Epileptiform After-Discharges as Rhythmic Oscillatory Transients.Frontiers in computational neuroscience · 2017Article
- Functional disconnection of axonal fibers generated by high frequency stimulation in the hippocampal CA1 region in-vivo.Brain research · 2013Article
- Clinical significance and developmental changes of auditory-language-related gamma activity.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2013Article
- High frequency stimulation extends the refractory period and generates axonal block in the rat hippocampus.Brain stimulationArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo study when afterdischarges (ADs) are more likely to occur during cortical stimulation.
methodsWe examined 6250 electrical stimulation trials in 13 patients with subdural electrodes, studying whether AD occurrence during a trial was influenced by electrode pair stimulated or AD occurrence during the previous trial. In total 545 electrodes were stimulated, 119 frontal (pre-perirolandic), 289 perirolandic, 36 parietal (post-perirolandic), 95 temporal, and 6 occipital.
resultsWhen the same electrode pair was stimulated as the prior trial, 19% produced ADs compared to 5% of trials when a different electrodes pair was stimulated (p<0.0001). When trials showed ADs, and the next trial stimulated the same electrode pair, ADs occurred in 46% of cases, compared to 13% of trials following trials without ADs (p<0.0001). AD probability decreased with increased inter-trial interval length only when the prior trial was at the same electrode pair and had produced an AD (p=0.001). AD probability increased with stimulation duration, whether the trial followed a trial with (p<0.001) or without (p<0.0001) an AD.
conclusionsADs were more likely to occur when an electrode pair showed ADs and was stimulated again, especially when stimulating after short inter-trial intervals or for longer duration. SIGNIFICANCE: When ADs occur, waiting about a minute before resuming stimulation might lessen the likelihood of AD recurrence.
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