ReviewHormones and behavior2010
The emergence of gonadal hormone influences on dopaminergic function during puberty.
Review in Hormones and behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 113 citations in OpenAlex.
- Characteristics of Executive Function in School-Aged Girls With Idiopathic Central Precocious Puberty.Brain and behavior · 2026Article
- Article
- Investigating the Characteristics of Pelvic Ultrasound in Girls With Their First Menstrual Cycle: A Two-Center Cross-Sectional Study.Health science reports · 2025Article
- The explore/exploit trade-off: An ecologically valid and translational framework that can advance mechanistic understanding of eating disorders.The International journal of eating disorders · 2024Article
- Article
- Latent class analysis to characterize neonatal risk for neurodevelopmental differences.Journal of child psychology and psychiatry, and allied disciplines · 2023Article
- Contributions of dopamine-related basal ganglia neurophysiology to the developmental effects of incentives on inhibitory control.Developmental cognitive neuroscience · 2022Article
- Transient serotonin depletion at adolescence, but not at early infancy, reduced subsequent anxiety-like behavior and alcohol intake in female mice.Psychopharmacology · 2021Article
- Trait negative affect interacts with ovarian hormones to predict risk for emotional eating.Clinical psychological science : a journal of the Association for Psychological Science · 2021Article
- Sex-specific associations between co-exposure to multiple metals and visuospatial learning in early adolescence.Translational psychiatry · 2020Article
- Sexual Differentiation and Substance Use: A Mini-Review.Endocrinology · 2020Review
- The relationship between pubertal hormones and brain plasticity: Implications for cognitive training in adolescence.Developmental cognitive neuroscience · 2020Review
- Cortical morphometry and structural connectivity relate to executive function and estradiol level in healthy adolescents.Brain and behavior · 2019Article
- Gonadal hormone contributions to individual differences in eating disorder risk.Current opinion in psychiatry · 2019Review
- Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation.Frontiers in psychiatry · 2019Article
- Ethanol actions on the ventral tegmental area: novel potential targets on reward pathway neurons.Psychopharmacology · 2018Review
- Biological Sex, Estradiol and Striatal Medium Spiny Neuron Physiology: A Mini-Review.Frontiers in cellular neuroscience · 2018Review
- Defining the Construct of Synthetic Androgen Intoxication: An Application of General Brain Arousal.Frontiers in psychology · 2018Article
- Adolescence and Reward: Making Sense of Neural and Behavioral Changes Amid the Chaos.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Review
- Sex moderates the impact of birth weight on child externalizing psychopathology.Journal of abnormal psychology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Adolescence is the developmental epoch during which children become adults-intellectually, physically, hormonally and socially. Brain development in critical areas is ongoing. Adolescents are risk-taking and novelty-seeking and they weigh positive experiences more heavily and negative experiences less than adults. This inherent behavioral bias can lead to risky behaviors like drug taking. Most drug addictions start during adolescence and early drug-taking is associated with an increased rate of drug abuse and dependence. The hormonal changes of puberty contribute to physical, emotional, intellectual and social changes during adolescence. These hormonal events do not just cause maturation of reproductive function and the emergence of secondary sex characteristics. They contribute to the appearance of sex differences in non-reproductive behaviors as well. Sex differences in drug use behaviors are among the latter. The male predominance in overall drug use appears by the end of adolescence, while girls develop the rapid progression from first use to dependence (telescoping) that represent a female-biased vulnerability. Sex differences in many behaviors including drug use have been attributed to social and cultural factors. A narrowing gap in drug use between adolescent boys and girls supports this thesis. However, some sex differences in addiction vulnerability reflect biologic differences in brain circuits involved in addiction. The purpose of this review is to summarize the contribution of sex differences in the function of ascending dopamine systems that are critical to reinforcement, to briefly summarize the behavioral, neurochemical and anatomical changes in brain dopaminergic functions related to addiction that occur during adolescence and to present new findings about the emergence of sex differences in dopaminergic function during adolescence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.