Evidence map›Paper›PMID 19898524›Full record

ReviewBiochemistry and cell biology = Biochimie et biologie cellulaire2009

Protection and replication of telomeres in fission yeast.

Bettina A Moser, Toru M Nakamura

Open access · greenAbstract readReview
In one paragraph

Review in Biochemistry and cell biology = Biochimie et biologie cellulaire, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Telomere Replication: Solving Multiple End Replication Problems.Frontiers in cell and developmental biology · 2021
    Review
  9. Review
  10. Article
  11. Tpz1Communications biology · 2019
    Article
  12. Article
  13. Emerging roles of CST in maintaining genome stability and human disease.Frontiers in bioscience (Landmark edition) · 2018
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Telomerase Mechanism of Telomere Synthesis.Annual review of biochemistry · 2017
    Review
  19. Article
  20. Timeless protection of telomeres.Current genetics · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bettina A MoserDepartment of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 S. Ashland Ave. MC669, Chicago, IL 60607, USA.
Toru M Nakamura
University of Illinois Chicago · US

Funding

Roles of Checkpoint and DNA Repair Proteins in Fission Yeast Telomere MaintenanceR01GM078253 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NAKAMURA, TORU · 2006 to 2019
$4.1M
NIGMS NIH HHS GM078253NIGMS NIH HHS R01 GM078253
6 · The paper itself

Abstract

Telomeres, the natural ends of linear chromosomes, must be protected and completely replicated to guarantee genomic stability in eukaryotic cells. However, the protected state of telomeres is not compatible with recruitment of telomerase, an enzyme responsible for extending telomeric G-rich repeats during S-phase; thus, telomeres must undergo switches from a protected state to an accessible state during the cell cycle. In this minireview, we will summarize recent advances in our understanding of proteins involved in the protection and replication of telomeres, and the way these factors are dynamically recruited to telomeres during the cell cycle. We will focus mainly on recent results from fission yeast Schizosaccharomyces pombe, and compare them with results from budding yeast Saccharomyces cerevisiae and mammalian cell studies. In addition, a model for the way in which fission yeast cells replicate telomeres will be presented.

Indexed as

DNA ReplicationGenomic InstabilityModels, BiologicalSchizosaccharomycesSchizosaccharomyces pombe ProteinsTelomeraseTelomereTelomere-Binding ProteinsSchizosaccharomyces pombe ProteinsStn1 protein, S pombeTelomeraseTelomere-Binding ProteinsTen1 protein, S pombe

Identifiers

PMID19898524
PMCPMC2854563
OpenAlexW616108462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.