Trial reportRetina (Philadelphia, Pa.)
The course of response to focal/grid photocoagulation for diabetic macular edema.
Trial report in Retina (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00442156 (The Course of Response to Focal Photocoagulation for Diabetic Macular Edema), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Course of Response to Focal Photocoagulation for Diabetic Macular Edema
Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Islets persisting on OCT macular thickness map after intravitreal injections unmask telangiectatic capillaries (TelCaps) in diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Trial
- Randomized trial evaluating short-term effects of intravitreal ranibizumab or triamcinolone acetonide on macular edema after focal/grid laser for diabetic macular edema in eyes also receiving panretinal photocoagulation.Retina (Philadelphia, Pa.) · 2011Trial
- Consensus-based recommendations for indications and procedures in retinal laser treatment of Telangiectatic capillaries (TelCaps) in vascular macular oedema: A Delphi study.Acta ophthalmologica · 2025Article
- REal-world treatment outcomes after delayed intRavitreal therapy in center-involving diabetic macular edema - RETORT study.International journal of retina and vitreous · 2023Article
- Statement of the German Ophthalmological Society, the German Retina Society, and the Professional Association of Ophthalmologists in Germany on treatment of diabetic macular edema : Dated August 2019.Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021Review
- [Statement of the German Ophthalmological Society, the Retinological Society and the Professional Association of Ophthalmologists in Germany on treatment of diabetic macular edema : Situation August 2019].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Review
- Teleophthalmology image-based navigated retinal laser therapy for diabetic macular edema: a concept of retinal telephotocoagulation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017Article
- The Role of Focal Laser in the Anti-Vascular Endothelial Growth Factor Era.Ophthalmology and eye diseases · 2017Review
- Recent advances in the management and understanding of diabetic retinopathy.F1000Research · 2017Review
- Efficacy and safety of topical difluprednate in persistent diabetic macular edema.International ophthalmology · 2016Article
- Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network.Singapore medical journal · 2015Review
- Three-dimensional imaging of the inner limiting membrane folding on the vitreomacular interface in diabetic macular edema.Japanese journal of ophthalmology · 2013Article
- Characterization of microaneurysm closure after focal laser photocoagulation in diabetic macular edema.American journal of ophthalmology · 2013Article
- Five-year visual outcome following laser photocoagulation of diabetic macular oedema.Eye (London, England) · 2011Article
- Ranibizumab for diabetic macular edema difficult to treat with focal/grid laser.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2010Article
- Macular laser photocoagulation in the management of diabetic macular edema: Still relevant in 2020?Taiwan journal of ophthalmologyReview
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purposeThe purpose of this study was to determine whether eyes with center-involved diabetic macular edema, treated with focal/grid photocoagulation, in which there is a reduction in central subfield thickness (CST) measured with optical coherence tomography after 16 weeks, will continue to improve if retreatment is deferred.
methodsThis is a prospective, multicenter, observational, single-group focal/grid photocoagulation study of 122 eyes with center-involved diabetic macular edema (optical coherence tomography CST > or =250 microm). At the 16-week visit and continuing every 8 weeks, eyes were assessed for retreatment and additional laser treatment was deferred if the visual acuity letter score improved > or =5 letters or optical coherence tomography CST decreased > or =10% compared with the visit 16 weeks prior.
resultsOf the 115 eyes that completed the 16-week visit, 54 (47%) had a decrease in CST by > or =10% compared with baseline. Of these, 26 (48%) had a CST > or =250 microm at 16 weeks and were evaluable at 32 weeks. Eleven (42%; 95% confidence interval, 23-63%) of the 26 eyes had a further decrease in CST > or =10% from 16 weeks to 32 weeks without further treatment.
conclusionSixteen weeks after focal/grid laser for diabetic macular edema in eyes with a definite reduction, but not resolution, of central edema, 23% to 63% likely will continue to improve without additional treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.