Evidence map›Paper›PMID 19897653›Full record

ArticleJournal of bacteriology2010

Promoter and riboswitch control of the Mg2+ transporter MgtA from Salmonella enterica.

Michael J Cromie, Eduardo A Groisman

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. How Bacterial Pathogens Coordinate Appetite with Virulence.Microbiology and molecular biology reviews : MMBR · 2023
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. How the PhoP/PhoQ System Controls Virulence and MgMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  12. Small proteins regulateProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Article
  14. Article
  15. Regulation of Bacterial Gene Expression by Transcription Attenuation.Microbiology and molecular biology reviews : MMBR · 2019
    Review
  16. Article
  17. Function analysis of 5'-UTR of the cellulosomalBiotechnology for biofuels · 2018
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael J CromieHoward Hughes Medical Institute, Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Eduardo A Groisman
Howard Hughes Medical Institute · US

Funding

REGULATION OF SALMONELLA VIRULENCE BY THE PHOP PROTEINR01AI049561 · NIAID · YALE UNIVERSITY · PI Eduardo Groisman · 2001 to 2026
$9.7M
Howard Hughes Medical InstituteNIAID NIH HHS AI49561NIAID NIH HHS R01 AI049561
6 · The paper itself

Abstract

The MgtA protein from Salmonella enterica serovar Typhimurium mediates Mg(2+) uptake from the periplasm into the cytoplasm. Here we report that the PhoP/PhoQ two-component regulatory system, which responds to periplasmic Mg(2+), governs mgtA transcription initiation at all investigated Mg(2+) concentrations and that the Mg(2+)-sensing 5' leader region of the mgtA gene controls transcription elongation into the mgtA coding region when Salmonella is grown in media with <50 muM Mg(2+). Overexpression of the Mg(2+) transporter CorA, which is believed to increase cytoplasmic Mg(2+) levels, decreased mgtA transcription in a manner dependent on a functional mgtA 5' leader.

Indexed as

Adenosine TriphosphatasesBacterial ProteinsBlotting, WesternGene Expression Regulation, BacterialMagnesiumMembrane Transport ProteinsPromoter Regions, GeneticSalmonella typhimuriumAdenosine TriphosphatasesBacterial ProteinsMagnesiumMembrane Transport ProteinsMgtA protein, bacteriaPhoP protein, BacteriaPhoQ protein, Bacteria

Identifiers

PMID19897653
PMCPMC2805325
OpenAlexW2145552975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.