ArticleNucleic acids research2010
T3DB: a comprehensively annotated database of common toxins and their targets.
Article in Nucleic acids research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Knowledge-Driven Approaches to Create the MTox700+ Metabolite Panel for Predicting Toxicity.Toxicological sciences : an official journal of the Society of Toxicology · 2022Pooled it
- Navigating through toxicological data: review of toxicological databases and sources in the interdisciplinary context including-chemicals, cosmetics, pharmaceuticals and forensics.Archives of toxicology · 2026Review
- Carcinogenicity prediction via multi-task learning of cross-organ representations with attention mechanisms.Briefings in bioinformatics · 2026Article
- Machine learning and free energy clustering reveal PAH protein binding linked to AD risk.iScience · 2026Article
- Structural Isomer Cumulative molecular fingerprinting method (SIC) for standardizing structural isomeric relationships.Communications chemistry · 2025Article
- Recent Advancements in the Diversification and Applications of Boron-Containing Compounds in Medicinal Chemistry.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole-Thiazole Hybrids as Potent Colon Cancer Inhibitors.ChemistryOpen · 2025Article
- Metabolomic Profiling of Ocular Fluid Identifies Host Response Factors for Risk Stratification in Bacterial Endophthalmitis.Investigative ophthalmology & visual science · 2025Article
- UVREK: Development and Analysis of an Expression Profile Knowledgebase of Biomolecules Induced by Ultraviolet Radiation Exposure.ACS omega · 2025Article
- A National Study of the Associations between Hormonal Modulators in Hydraulic Fracturing Fluid Chemicals and Birth Outcomes in the United States of America: A County-Level Analysis.Environmental health perspectives · 2024Article
- Genetically engineered eucalyptus expressing pesticidal proteins fromFrontiers in bioengineering and biotechnology · 2024Article
- Clustering Protein Binding Pockets and Identifying Potential Drug Interactions: A Novel Ligand-Based Featurization Method.Journal of chemical information and modeling · 2023Article
- Hepatic cholesterol biosynthesis and dioxin-induced dysregulation: A multiscale computational approach.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023Article
- Towards interoperability in infection control: a standard data model for microbiology.Scientific data · 2023Article
- TCMSTD 1.0: a systematic analysis of the traditional Chinese medicine system toxicology database.Science China. Life sciences · 2023Article
- Exposome epidemiology for suspect environmental chemical exposures during pregnancy linked to subsequent breast cancer diagnosis.Environment international · 2023Article
- Molecular determinants of acrylamide neurotoxicity through covalent docking.Frontiers in pharmacology · 2023Article
- Tox21Enricher-Shiny: an R Shiny application for toxicity functional annotation analysis.Frontiers in toxicology · 2023Article
- Review
- Predicting Dose-Range Chemical Toxicity using Novel Hybrid Deep Machine-Learning Method.Toxics · 2022Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
In an effort to capture meaningful biological, chemical and mechanistic information about clinically relevant, commonly encountered or important toxins, we have developed the Toxin and Toxin-Target Database (T3DB). The T3DB is a unique bioinformatics resource that compiles comprehensive information about common or ubiquitous toxins and their toxin-targets into a single electronic repository. The database currently contains over 2900 small molecule and peptide toxins, 1300 toxin-targets and more than 33,000 toxin-target associations. Each T3DB record (ToxCard) contains over 80 data fields providing detailed information on chemical properties and descriptors, toxicity values, protein and gene sequences (for both targets and toxins), molecular and cellular interaction data, toxicological data, mechanistic information and references. This information has been manually extracted and manually verified from numerous sources, including other electronic databases, government documents, textbooks and scientific journals. A key focus of the T3DB is on providing 'depth' over 'breadth' with detailed descriptions, mechanisms of action, and information on toxins and toxin-targets. T3DB is fully searchable and supports extensive text, sequence, chemical structure and relational query searches, similar to those found in the Human Metabolome Database (HMDB) and DrugBank. Potential applications of the T3DB include clinical metabolomics, toxin target prediction, toxicity prediction and toxicology education. The T3DB is available online at http://www.t3db.org.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.